Composite liver tumors: A radiologic-pathologic correlation

Composite liver tumors: A radiologic-pathologic correlation

Bi-phenotypic neoplasm refers to tumors derived from a common cancer stem cell with unique capability to differentiate histologically into two distinct tumor types. Bi-phenotypic hepatocellular carcinoma-cholangiocarcinoma (HCC-CC), although a rare tumor, is important for clinicians to recognize, si...

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Bibliographic Details
Main Authors: Megha Nayyar, David K. Imagawa, Temel Tirkes, Aram N. Demirjian, Roozbeh Houshyar, Kumar Sandrasegaran, Chaitali S. Nangia, Tara Seery, P Bhargava, Joon II Choi, Chandana Lall
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2014-12-01
Series:Clinical and Molecular Hepatology
Subjects:
Hepatoceullular carcinoma
Cholangiocarcinoma
Bi-phenotypic tumors
Computed tomography, Magnetic resonance imaging
Online Access:http://e-cmh.org/upload/pdf/cmh-20-406.pdf
Description
Summary:Bi-phenotypic neoplasm refers to tumors derived from a common cancer stem cell with unique capability to differentiate histologically into two distinct tumor types. Bi-phenotypic hepatocellular carcinoma-cholangiocarcinoma (HCC-CC), although a rare tumor, is important for clinicians to recognize, since treatment options targeting both elements of the tumor are crucial. Imaging findings of bi-phenotypic HCC-CC are not specific and include features of both HCC and CC. A combination of imaging and immuno-histochemical analysis is usually needed to make the diagnosis.
ISSN:2287-2728
2287-285X

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