Global Transcriptome Changes of Biofilm-Forming Staphylococcus epidermidis Responding to Total Alkaloids of Sophorea alopecuroides

Transcriptome changes of biofilm-forming Staphylococcus epidermidis response to total alkaloids of Sophorea alopecuroides was observed. Bioinformatic analyses were further used to compare the differential gene expression between control and the treated samples. It was found that 282 genes were diffe...

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Main Authors:	CUI-PING GUAN, HUI-XIA LUO, H.E. FANG, XUE-ZHANG ZHOU
Format:	Article
Language:	English
Published:	Exeley Inc. 2018-06-01
Series:	Polish Journal of Microbiology
Subjects:	Staphylococcus epidermidis sulfur metabolism total alkaloids of Sophorea alopecuroides transcriptome
Online Access:	https://www.exeley.com/exeley/journals/polish_journal_of_microbiology/67/2/pdf/10.21307_pjm-2018-024.pdf

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spelling	doaj-c2ba8397d6494262bcc007b7776ca8d72020-11-25T00:08:43ZengExeley Inc.Polish Journal of Microbiology1733-13312544-46462018-06-0167210.21307/pjm-2018-024Global Transcriptome Changes of Biofilm-Forming Staphylococcus epidermidis Responding to Total Alkaloids of Sophorea alopecuroidesCUI-PING GUAN0HUI-XIA LUO1H.E. FANG2XUE-ZHANG ZHOU3Key Laboratory of the Ministry of Education for the Conservation and Utilization of Special Biological Resources in Western China, Ningxia University,Yinchuan, Ningxia,ChinaKey Laboratory of the Ministry of Education for the Conservation and Utilization of Special Biological Resources in Western China, Ningxia University,Yinchuan, Ningxia,ChinaKey Laboratory of the Ministry of Education for the Conservation and Utilization of Special Biological Resources in Western China, Ningxia University,Yinchuan, Ningxia,ChinaKey Laboratory of the Ministry of Education for the Conservation and Utilization of Special Biological Resources in Western China, Ningxia University,Yinchuan, Ningxia,ChinaTranscriptome changes of biofilm-forming Staphylococcus epidermidis response to total alkaloids of Sophorea alopecuroides was observed. Bioinformatic analyses were further used to compare the differential gene expression between control and the treated samples. It was found that 282 genes were differentially expressed, with 92 up-regulated and 190 down-regulated. These involved down-regulation of the sulfur metabolism pathway. It was suggested that inhibitory effects on Staphylococcus epidermidis and its biofilm formation of the total alkaloids of S. alopecuroides was mainly due to the regulation of the sulfur metabolism pathways of S. epidermidis.https://www.exeley.com/exeley/journals/polish_journal_of_microbiology/67/2/pdf/10.21307_pjm-2018-024.pdfStaphylococcus epidermidissulfur metabolismtotal alkaloids of Sophorea alopecuroidestranscriptome
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	CUI-PING GUAN HUI-XIA LUO H.E. FANG XUE-ZHANG ZHOU
spellingShingle	CUI-PING GUAN HUI-XIA LUO H.E. FANG XUE-ZHANG ZHOU Global Transcriptome Changes of Biofilm-Forming Staphylococcus epidermidis Responding to Total Alkaloids of Sophorea alopecuroides Polish Journal of Microbiology Staphylococcus epidermidis sulfur metabolism total alkaloids of Sophorea alopecuroides transcriptome
author_facet	CUI-PING GUAN HUI-XIA LUO H.E. FANG XUE-ZHANG ZHOU
author_sort	CUI-PING GUAN
title	Global Transcriptome Changes of Biofilm-Forming Staphylococcus epidermidis Responding to Total Alkaloids of Sophorea alopecuroides
title_short	Global Transcriptome Changes of Biofilm-Forming Staphylococcus epidermidis Responding to Total Alkaloids of Sophorea alopecuroides
title_full	Global Transcriptome Changes of Biofilm-Forming Staphylococcus epidermidis Responding to Total Alkaloids of Sophorea alopecuroides
title_fullStr	Global Transcriptome Changes of Biofilm-Forming Staphylococcus epidermidis Responding to Total Alkaloids of Sophorea alopecuroides
title_full_unstemmed	Global Transcriptome Changes of Biofilm-Forming Staphylococcus epidermidis Responding to Total Alkaloids of Sophorea alopecuroides
title_sort	global transcriptome changes of biofilm-forming staphylococcus epidermidis responding to total alkaloids of sophorea alopecuroides
publisher	Exeley Inc.
series	Polish Journal of Microbiology
issn	1733-1331 2544-4646
publishDate	2018-06-01
description	Transcriptome changes of biofilm-forming Staphylococcus epidermidis response to total alkaloids of Sophorea alopecuroides was observed. Bioinformatic analyses were further used to compare the differential gene expression between control and the treated samples. It was found that 282 genes were differentially expressed, with 92 up-regulated and 190 down-regulated. These involved down-regulation of the sulfur metabolism pathway. It was suggested that inhibitory effects on Staphylococcus epidermidis and its biofilm formation of the total alkaloids of S. alopecuroides was mainly due to the regulation of the sulfur metabolism pathways of S. epidermidis.
topic	Staphylococcus epidermidis sulfur metabolism total alkaloids of Sophorea alopecuroides transcriptome
url	https://www.exeley.com/exeley/journals/polish_journal_of_microbiology/67/2/pdf/10.21307_pjm-2018-024.pdf
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Global Transcriptome Changes of Biofilm-Forming Staphylococcus epidermidis Responding to Total Alkaloids of Sophorea alopecuroides

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