Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy
Abstract Background Skeletal muscle atrophy is a pathological condition that contributes to morbidity in a variety of conditions including denervation, cachexia, and aging. Muscle atrophy is characterized as decreased muscle fiber cross-sectional area and protein content due, in part, to the proteol...
Main Authors: | Neena Lala-Tabbert, Rim Lejmi-Mrad, Kristen Timusk, Marina Fukano, Janelle Holbrook, Martine St-Jean, Eric C. LaCasse, Robert G. Korneluk |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-05-01
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Series: | Skeletal Muscle |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13395-019-0201-6 |
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