ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams

The main effort of the laser-driven ion acceleration community is aimed at improving particle beam features (in terms of final maximum energy, particle charge, and beam divergence) and to demonstrate reliable approaches for use for multidisciplinary applications. An ion acceleration target area base...

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Main Authors: Giuseppe A. P. Cirrone, Giada Petringa, Roberto Catalano, Francesco Schillaci, Luciano Allegra, Antonino Amato, Renato Avolio, Michele Costa, Giacomo Cuttone, Antonin Fajstavr, Giuseppe Gallo, Lorenzo Giuffrida, Mariacristina Guarrera, Georg Korn, Giuseppina Larosa, Renata Leanza, Enzo Lo Vecchio, Gustavo Messina, Giuliana Milluzzo, Veronika Olsovcova, Salvatore Pulvirenti, Jan Pipek, Francesco Romano, Daniele Rizzo, Antonio D. Russo, S. Salamone, Valentina Scuderi, Andriy Velyhan, Salvatore Vinciguerra, Martina Zakova, Emilio Zappalà, Daniele Margarone
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2020.564907/full
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author Giuseppe A. P. Cirrone
Giada Petringa
Roberto Catalano
Francesco Schillaci
Luciano Allegra
Antonino Amato
Renato Avolio
Michele Costa
Giacomo Cuttone
Antonin Fajstavr
Giuseppe Gallo
Lorenzo Giuffrida
Mariacristina Guarrera
Georg Korn
Giuseppina Larosa
Renata Leanza
Enzo Lo Vecchio
Gustavo Messina
Giuliana Milluzzo
Giuliana Milluzzo
Veronika Olsovcova
Salvatore Pulvirenti
Jan Pipek
Francesco Romano
Daniele Rizzo
Antonio D. Russo
S. Salamone
Valentina Scuderi
Andriy Velyhan
Salvatore Vinciguerra
Martina Zakova
Martina Zakova
Emilio Zappalà
Daniele Margarone
Daniele Margarone
spellingShingle Giuseppe A. P. Cirrone
Giada Petringa
Roberto Catalano
Francesco Schillaci
Luciano Allegra
Antonino Amato
Renato Avolio
Michele Costa
Giacomo Cuttone
Antonin Fajstavr
Giuseppe Gallo
Lorenzo Giuffrida
Mariacristina Guarrera
Georg Korn
Giuseppina Larosa
Renata Leanza
Enzo Lo Vecchio
Gustavo Messina
Giuliana Milluzzo
Giuliana Milluzzo
Veronika Olsovcova
Salvatore Pulvirenti
Jan Pipek
Francesco Romano
Daniele Rizzo
Antonio D. Russo
S. Salamone
Valentina Scuderi
Andriy Velyhan
Salvatore Vinciguerra
Martina Zakova
Martina Zakova
Emilio Zappalà
Daniele Margarone
Daniele Margarone
ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams
Frontiers in Physics
protontherapy
dosimetry
Monte Carlo
laser-driven
ELIMED
laser-driven ions
author_facet Giuseppe A. P. Cirrone
Giada Petringa
Roberto Catalano
Francesco Schillaci
Luciano Allegra
Antonino Amato
Renato Avolio
Michele Costa
Giacomo Cuttone
Antonin Fajstavr
Giuseppe Gallo
Lorenzo Giuffrida
Mariacristina Guarrera
Georg Korn
Giuseppina Larosa
Renata Leanza
Enzo Lo Vecchio
Gustavo Messina
Giuliana Milluzzo
Giuliana Milluzzo
Veronika Olsovcova
Salvatore Pulvirenti
Jan Pipek
Francesco Romano
Daniele Rizzo
Antonio D. Russo
S. Salamone
Valentina Scuderi
Andriy Velyhan
Salvatore Vinciguerra
Martina Zakova
Martina Zakova
Emilio Zappalà
Daniele Margarone
Daniele Margarone
author_sort Giuseppe A. P. Cirrone
title ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams
title_short ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams
title_full ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams
title_fullStr ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams
title_full_unstemmed ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion Beams
title_sort elimed-elimaia: the first open user irradiation beamline for laser-plasma-accelerated ion beams
publisher Frontiers Media S.A.
series Frontiers in Physics
issn 2296-424X
publishDate 2020-11-01
description The main effort of the laser-driven ion acceleration community is aimed at improving particle beam features (in terms of final maximum energy, particle charge, and beam divergence) and to demonstrate reliable approaches for use for multidisciplinary applications. An ion acceleration target area based on unique laser capabilities is available at ELI-Beamlines (Extreme Light Infrastructure) in the Czech Republic; it is called ELIMAIA (ELI Multidisciplinary Applications of laser-Ion Acceleration) and aims to provide stable and characterized beams of particles accelerated by high-power lasers to offer them to the user community for interdisciplinary studies. The ELIMAIA section dedicated to ion focusing, selection, characterization, and irradiation is named ELIMED (ELI MEDical and multidisciplinary applications). Thanks to ELIMED, very high-dose-rate (around Gy/min) controlled proton and ion beams, with energy levels ranging from 5 to 250 MeV, will be transported to an in-air section dedicated to absolute and relative dosimetry of the laser-generated ions. A transmission dual-gap air ionization chamber will allow an on-line, non-destructive characterization of the ion dose at the user sample irradiation point. The uncertainty in the final dose released onto the sample is expected to be well below 5%. An ELIMED radiobiology pilot experiment is scheduled for 2021, during which in-vitro cell irradiations will be carried out with well-controlled proton beams. In this work, the status of the ELIMED/ELIMAIA beamline will be described along with a complete definition of the main dosimetric systems and of their calibrations carried out at conventional accelerators.
topic protontherapy
dosimetry
Monte Carlo
laser-driven
ELIMED
laser-driven ions
url https://www.frontiersin.org/articles/10.3389/fphy.2020.564907/full
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spelling doaj-c2c2094d6f734df59433ad2af007e3f32020-11-25T04:03:11ZengFrontiers Media S.A.Frontiers in Physics2296-424X2020-11-01810.3389/fphy.2020.564907564907ELIMED-ELIMAIA: The First Open User Irradiation Beamline for Laser-Plasma-Accelerated Ion BeamsGiuseppe A. P. Cirrone0Giada Petringa1Roberto Catalano2Francesco Schillaci3Luciano Allegra4Antonino Amato5Renato Avolio6Michele Costa7Giacomo Cuttone8Antonin Fajstavr9Giuseppe Gallo10Lorenzo Giuffrida11Mariacristina Guarrera12Georg Korn13Giuseppina Larosa14Renata Leanza15Enzo Lo Vecchio16Gustavo Messina17Giuliana Milluzzo18Giuliana Milluzzo19Veronika Olsovcova20Salvatore Pulvirenti21Jan Pipek22Francesco Romano23Daniele Rizzo24Antonio D. Russo25S. Salamone26Valentina Scuderi27Andriy Velyhan28Salvatore Vinciguerra29Martina Zakova30Martina Zakova31Emilio Zappalà32Daniele Margarone33Daniele Margarone34Laboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyELI-Beamlines, Institute of Physics (FZU), Czech Academy of Sciences, Prague, CzechiaLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyELI-Beamlines, Institute of Physics (FZU), Czech Academy of Sciences, Prague, CzechiaLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyELI-Beamlines, Institute of Physics (FZU), Czech Academy of Sciences, Prague, CzechiaLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyELI-Beamlines, Institute of Physics (FZU), Czech Academy of Sciences, Prague, CzechiaLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyCentre for Plasma Physics, Queen's University of Belfast, Belfast, United KingdomELI-Beamlines, Institute of Physics (FZU), Czech Academy of Sciences, Prague, CzechiaLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyELI-Beamlines, Institute of Physics (FZU), Czech Academy of Sciences, Prague, CzechiaLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyELI-Beamlines, Institute of Physics (FZU), Czech Academy of Sciences, Prague, CzechiaFNSPE, Czech Technical University in Prague, Prague, CzechiaLaboratori Nazionali del Sud Istituto Nazionale di Fisica Nucleare (INFN-LNS), Catania, ItalyELI-Beamlines, Institute of Physics (FZU), Czech Academy of Sciences, Prague, CzechiaCentre for Plasma Physics, Queen's University of Belfast, Belfast, United KingdomThe main effort of the laser-driven ion acceleration community is aimed at improving particle beam features (in terms of final maximum energy, particle charge, and beam divergence) and to demonstrate reliable approaches for use for multidisciplinary applications. An ion acceleration target area based on unique laser capabilities is available at ELI-Beamlines (Extreme Light Infrastructure) in the Czech Republic; it is called ELIMAIA (ELI Multidisciplinary Applications of laser-Ion Acceleration) and aims to provide stable and characterized beams of particles accelerated by high-power lasers to offer them to the user community for interdisciplinary studies. The ELIMAIA section dedicated to ion focusing, selection, characterization, and irradiation is named ELIMED (ELI MEDical and multidisciplinary applications). Thanks to ELIMED, very high-dose-rate (around Gy/min) controlled proton and ion beams, with energy levels ranging from 5 to 250 MeV, will be transported to an in-air section dedicated to absolute and relative dosimetry of the laser-generated ions. A transmission dual-gap air ionization chamber will allow an on-line, non-destructive characterization of the ion dose at the user sample irradiation point. The uncertainty in the final dose released onto the sample is expected to be well below 5%. An ELIMED radiobiology pilot experiment is scheduled for 2021, during which in-vitro cell irradiations will be carried out with well-controlled proton beams. In this work, the status of the ELIMED/ELIMAIA beamline will be described along with a complete definition of the main dosimetric systems and of their calibrations carried out at conventional accelerators.https://www.frontiersin.org/articles/10.3389/fphy.2020.564907/fullprotontherapydosimetryMonte Carlolaser-drivenELIMEDlaser-driven ions