Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling
A novel banana-shaped molecule using 2,8-Dimethyl-6<i>H</i>,12<i>H</i>-5,11-methanodibenzo [<i>b,f</i>] [1,5]diazocine (Tröger’s base) as bent-core was synthesized via double Carbon-Carbon cross-coupling reaction. The double Sonogashira cross-co...
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Online Access: | https://www.mdpi.com/1420-3049/24/4/698 |
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doaj-c2cdb806bb804f5a8726f3f33a5e857f2020-11-25T01:59:03ZengMDPI AGMolecules1420-30492019-02-0124469810.3390/molecules24040698molecules24040698Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-CouplingBingchuan Yang0Guodong Shen1Xianqiang Huang2Rutao Liu3School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252000, ChinaSchool of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252000, ChinaSchool of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252000, ChinaSchool of Environmental Science and Engineering, Shandong University, Jinan 250100, ChinaA novel banana-shaped molecule using 2,8-Dimethyl-6<i>H</i>,12<i>H</i>-5,11-methanodibenzo [<i>b,f</i>] [1,5]diazocine (Tröger’s base) as bent-core was synthesized via double Carbon-Carbon cross-coupling reaction. The double Sonogashira cross-coupling reaction was optimized by using Pd(PPh<sub>3</sub>)<sub>2</sub>Cl<sub>2</sub> as catalyst, CuI as cocatalyst and diisopropylamine as base in place of triethylamine. The structure of this compound was confirmed by <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, Fourier transform infrared (FT-IR) spectroscopy and mass spectrometry.https://www.mdpi.com/1420-3049/24/4/698bent-coreTröger’s basedouble Sonogashira coupling |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bingchuan Yang Guodong Shen Xianqiang Huang Rutao Liu |
spellingShingle |
Bingchuan Yang Guodong Shen Xianqiang Huang Rutao Liu Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling Molecules bent-core Tröger’s base double Sonogashira coupling |
author_facet |
Bingchuan Yang Guodong Shen Xianqiang Huang Rutao Liu |
author_sort |
Bingchuan Yang |
title |
Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling |
title_short |
Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling |
title_full |
Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling |
title_fullStr |
Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling |
title_full_unstemmed |
Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling |
title_sort |
design and synthesis of a novel banana-shaped functional molecule via double cross-coupling |
publisher |
MDPI AG |
series |
Molecules |
issn |
1420-3049 |
publishDate |
2019-02-01 |
description |
A novel banana-shaped molecule using 2,8-Dimethyl-6<i>H</i>,12<i>H</i>-5,11-methanodibenzo [<i>b,f</i>] [1,5]diazocine (Tröger’s base) as bent-core was synthesized via double Carbon-Carbon cross-coupling reaction. The double Sonogashira cross-coupling reaction was optimized by using Pd(PPh<sub>3</sub>)<sub>2</sub>Cl<sub>2</sub> as catalyst, CuI as cocatalyst and diisopropylamine as base in place of triethylamine. The structure of this compound was confirmed by <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, Fourier transform infrared (FT-IR) spectroscopy and mass spectrometry. |
topic |
bent-core Tröger’s base double Sonogashira coupling |
url |
https://www.mdpi.com/1420-3049/24/4/698 |
work_keys_str_mv |
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