Production of monoclonal antibody to MSP-2 and evaluation of different domains of the molecule
Background: Plasmodiom falciparum MSP-2 is taken into accout as one of the candidates of vaccine agaist malaria and various studies indicated immunizing effect of different domains of the molecule. Monoclonal antibody against MSP-2 is a confident and definite method to confirm this Immunization. Mat...
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Lorestan University of Medical Science
2009-04-01
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doaj-c2efc2ea25864356b2911df8efb1065e2020-11-24T21:47:05ZfasLorestan University of Medical ScienceYafteh1563-07732009-04-011114348Production of monoclonal antibody to MSP-2 and evaluation of different domains of the moleculeafra Khosravi0eghbaleh Asadollahi1poul Hommel2 Background: Plasmodiom falciparum MSP-2 is taken into accout as one of the candidates of vaccine agaist malaria and various studies indicated immunizing effect of different domains of the molecule. Monoclonal antibody against MSP-2 is a confident and definite method to confirm this Immunization. Materials and Methods: P. falciparum Parasite was Prepared in a Culture in CludingRPMI1640 and Schizontantingens extracted and injected into the mice. Then B Lyphocytes of immunized mice were extracted from their spleen and the fusion was Performed using NS-1 and monoclonal antibody to MSP-2 was Produced. Results: Anumber of monoclonal antibody to MSP-2 weres Produced which confirmed efficiency and Immunizing effects of various domains of MSP-2 molecule.http://yafte.lums.ac.ir/browse.php?a_code=A-10-1-111&slc_lang=en&sid=1MSP-2 Immunization Plasmodium Falciparum Malaria |
collection |
DOAJ |
language |
fas |
format |
Article |
sources |
DOAJ |
author |
afra Khosravi eghbaleh Asadollahi poul Hommel |
spellingShingle |
afra Khosravi eghbaleh Asadollahi poul Hommel Production of monoclonal antibody to MSP-2 and evaluation of different domains of the molecule Yafteh MSP-2 Immunization Plasmodium Falciparum Malaria |
author_facet |
afra Khosravi eghbaleh Asadollahi poul Hommel |
author_sort |
afra Khosravi |
title |
Production of monoclonal antibody to MSP-2 and evaluation of different domains of the molecule |
title_short |
Production of monoclonal antibody to MSP-2 and evaluation of different domains of the molecule |
title_full |
Production of monoclonal antibody to MSP-2 and evaluation of different domains of the molecule |
title_fullStr |
Production of monoclonal antibody to MSP-2 and evaluation of different domains of the molecule |
title_full_unstemmed |
Production of monoclonal antibody to MSP-2 and evaluation of different domains of the molecule |
title_sort |
production of monoclonal antibody to msp-2 and evaluation of different domains of the molecule |
publisher |
Lorestan University of Medical Science |
series |
Yafteh |
issn |
1563-0773 |
publishDate |
2009-04-01 |
description |
Background: Plasmodiom falciparum MSP-2 is taken into accout as one of the candidates of vaccine agaist malaria and various studies indicated immunizing effect of different domains of the molecule. Monoclonal antibody against MSP-2 is a confident and definite method to confirm this Immunization.
Materials and Methods: P. falciparum Parasite was Prepared in a Culture in CludingRPMI1640 and Schizontantingens extracted and injected into the mice. Then B Lyphocytes of immunized mice were extracted from their spleen and the fusion was Performed using NS-1 and monoclonal antibody to MSP-2 was Produced.
Results: Anumber of monoclonal antibody to MSP-2 weres Produced which confirmed efficiency and Immunizing effects of various domains of MSP-2 molecule. |
topic |
MSP-2 Immunization Plasmodium Falciparum Malaria |
url |
http://yafte.lums.ac.ir/browse.php?a_code=A-10-1-111&slc_lang=en&sid=1 |
work_keys_str_mv |
AT afrakhosravi productionofmonoclonalantibodytomsp2andevaluationofdifferentdomainsofthemolecule AT eghbalehasadollahi productionofmonoclonalantibodytomsp2andevaluationofdifferentdomainsofthemolecule AT poulhommel productionofmonoclonalantibodytomsp2andevaluationofdifferentdomainsofthemolecule |
_version_ |
1725899425648214016 |