Systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resection
Background Gastroduodenal artery (GDA) pseudoaneurysm is a serious complication following pancreatic resection, associated with high morbidity and mortality rates. This review aimed to report the incidence of GDA pseudoaneurysm after pancreatic surgery, and describe clinical presentation and managem...
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Online Access: | https://doi.org/10.1002/bjs5.50210 |
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doaj-c2f5a08b6c4f41f2a4eb8d4d848bf7752021-04-02T07:10:23ZengOxford University PressBJS Open2474-98422019-12-013673574210.1002/bjs5.50210Systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resectionB. Brodie0H. M. Kocher1Barts and the London School of Medicine and Dentistry London UKCentre for Tumour Biology, Barts Cancer Institute Queen Mary University of London London UKBackground Gastroduodenal artery (GDA) pseudoaneurysm is a serious complication following pancreatic resection, associated with high morbidity and mortality rates. This review aimed to report the incidence of GDA pseudoaneurysm after pancreatic surgery, and describe clinical presentation and management. Methods MEDLINE and Embase were searched systematically for clinical studies evaluating postoperative GDA pseudoaneurysm. Incidence was calculated by dividing total number of GDA pseudoaneurysms by the total number of pancreatic operations. Additional qualitative data related to GDA pseudoaneurysm presentation and management following pancreatic resection were extracted and reviewed from individual reports. Results Nine studies were selected for systematic review involving 4227 pancreatic operations with 55 GDA pseudoaneurysms, with a reported incidence of 1·3 (range 0·2–8·3) per cent. Additional data were extracted from 39 individual examples of GDA pseudoaneurysm from 14 studies. The median time for haemorrhage after surgery was at 15 (range 4–210) days. A preceding complication in the postoperative period was documented in four of 21 patients (67 per cent), and sentinel bleeding was observed in 14 of 20 patients (70 per cent). Postoperative complications after pseudoaneurysm management occurred in two‐thirds of the patients (14 of 21). The overall survival rate was 85 per cent (33 of 39). Conclusion GDA pseudoaneurysm is a rare yet serious cause of haemorrhage after pancreatic surgery, with high mortality. The majority of the patients had a preceding complication. Sentinel bleeding was an important clinical indicator.https://doi.org/10.1002/bjs5.50210 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
B. Brodie H. M. Kocher |
spellingShingle |
B. Brodie H. M. Kocher Systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resection BJS Open |
author_facet |
B. Brodie H. M. Kocher |
author_sort |
B. Brodie |
title |
Systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resection |
title_short |
Systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resection |
title_full |
Systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resection |
title_fullStr |
Systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resection |
title_full_unstemmed |
Systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resection |
title_sort |
systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resection |
publisher |
Oxford University Press |
series |
BJS Open |
issn |
2474-9842 |
publishDate |
2019-12-01 |
description |
Background Gastroduodenal artery (GDA) pseudoaneurysm is a serious complication following pancreatic resection, associated with high morbidity and mortality rates. This review aimed to report the incidence of GDA pseudoaneurysm after pancreatic surgery, and describe clinical presentation and management. Methods MEDLINE and Embase were searched systematically for clinical studies evaluating postoperative GDA pseudoaneurysm. Incidence was calculated by dividing total number of GDA pseudoaneurysms by the total number of pancreatic operations. Additional qualitative data related to GDA pseudoaneurysm presentation and management following pancreatic resection were extracted and reviewed from individual reports. Results Nine studies were selected for systematic review involving 4227 pancreatic operations with 55 GDA pseudoaneurysms, with a reported incidence of 1·3 (range 0·2–8·3) per cent. Additional data were extracted from 39 individual examples of GDA pseudoaneurysm from 14 studies. The median time for haemorrhage after surgery was at 15 (range 4–210) days. A preceding complication in the postoperative period was documented in four of 21 patients (67 per cent), and sentinel bleeding was observed in 14 of 20 patients (70 per cent). Postoperative complications after pseudoaneurysm management occurred in two‐thirds of the patients (14 of 21). The overall survival rate was 85 per cent (33 of 39). Conclusion GDA pseudoaneurysm is a rare yet serious cause of haemorrhage after pancreatic surgery, with high mortality. The majority of the patients had a preceding complication. Sentinel bleeding was an important clinical indicator. |
url |
https://doi.org/10.1002/bjs5.50210 |
work_keys_str_mv |
AT bbrodie systematicreviewoftheincidencepresentationandmanagementofgastroduodenalarterypseudoaneurysmafterpancreaticresection AT hmkocher systematicreviewoftheincidencepresentationandmanagementofgastroduodenalarterypseudoaneurysmafterpancreaticresection |
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