A Protocol for the Use of Case Reports/Studies and Case Series in Systematic Reviews for Clinical Toxicology
Introduction: Systematic reviews are routinely used to synthesize current science and evaluate the evidential strength and quality of resulting recommendations. For specific events, such as rare acute poisonings or preliminary reports of new drugs, we posit that case reports/studies and case series...
Main Authors: | , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-09-01
|
Series: | Frontiers in Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2021.708380/full |
id |
doaj-c3113414e14d4d27a491496072bd089d |
---|---|
record_format |
Article |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Aboubakari Nambiema Grace Sembajwe Juleen Lam Tracey Woodruff Daniele Mandrioli Nicholas Chartres Marc Fadel Adrien Le Guillou Remi Valter Marie Deguigne Marion Legeay Chloe Bruneau Gaël Le Roux Gaël Le Roux Alexis Descatha Alexis Descatha |
spellingShingle |
Aboubakari Nambiema Grace Sembajwe Juleen Lam Tracey Woodruff Daniele Mandrioli Nicholas Chartres Marc Fadel Adrien Le Guillou Remi Valter Marie Deguigne Marion Legeay Chloe Bruneau Gaël Le Roux Gaël Le Roux Alexis Descatha Alexis Descatha A Protocol for the Use of Case Reports/Studies and Case Series in Systematic Reviews for Clinical Toxicology Frontiers in Medicine toxicology epidemiology public health protocol systematic review case reports/studies |
author_facet |
Aboubakari Nambiema Grace Sembajwe Juleen Lam Tracey Woodruff Daniele Mandrioli Nicholas Chartres Marc Fadel Adrien Le Guillou Remi Valter Marie Deguigne Marion Legeay Chloe Bruneau Gaël Le Roux Gaël Le Roux Alexis Descatha Alexis Descatha |
author_sort |
Aboubakari Nambiema |
title |
A Protocol for the Use of Case Reports/Studies and Case Series in Systematic Reviews for Clinical Toxicology |
title_short |
A Protocol for the Use of Case Reports/Studies and Case Series in Systematic Reviews for Clinical Toxicology |
title_full |
A Protocol for the Use of Case Reports/Studies and Case Series in Systematic Reviews for Clinical Toxicology |
title_fullStr |
A Protocol for the Use of Case Reports/Studies and Case Series in Systematic Reviews for Clinical Toxicology |
title_full_unstemmed |
A Protocol for the Use of Case Reports/Studies and Case Series in Systematic Reviews for Clinical Toxicology |
title_sort |
protocol for the use of case reports/studies and case series in systematic reviews for clinical toxicology |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Medicine |
issn |
2296-858X |
publishDate |
2021-09-01 |
description |
Introduction: Systematic reviews are routinely used to synthesize current science and evaluate the evidential strength and quality of resulting recommendations. For specific events, such as rare acute poisonings or preliminary reports of new drugs, we posit that case reports/studies and case series (human subjects research with no control group) may provide important evidence for systematic reviews. Our aim, therefore, is to present a protocol that uses rigorous selection criteria, to distinguish high quality case reports/studies and case series for inclusion in systematic reviews.Methods: This protocol will adapt the existing Navigation Guide methodology for specific inclusion of case studies. The usual procedure for systematic reviews will be followed. Case reports/studies and case series will be specified in the search strategy and included in separate sections. Data from these sources will be extracted and where possible, quantitatively synthesized. Criteria for integrating cases reports/studies and case series into the overall body of evidence are that these studies will need to be well-documented, scientifically rigorous, and follow ethical practices. The instructions and standards for evaluating risk of bias will be based on the Navigation Guide. The risk of bias, quality of evidence and the strength of recommendations will be assessed by two independent review teams that are blinded to each other.Conclusion: This is a protocol specified for systematic reviews that use case reports/studies and case series to evaluate the quality of evidence and strength of recommendations in disciplines like clinical toxicology, where case reports/studies are the norm. |
topic |
toxicology epidemiology public health protocol systematic review case reports/studies |
url |
https://www.frontiersin.org/articles/10.3389/fmed.2021.708380/full |
work_keys_str_mv |
AT aboubakarinambiema aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT gracesembajwe aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT juleenlam aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT traceywoodruff aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT danielemandrioli aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT nicholaschartres aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT marcfadel aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT adrienleguillou aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT remivalter aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT mariedeguigne aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT marionlegeay aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT chloebruneau aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT gaelleroux aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT gaelleroux aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT alexisdescatha aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT alexisdescatha aprotocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT aboubakarinambiema protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT gracesembajwe protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT juleenlam protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT traceywoodruff protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT danielemandrioli protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT nicholaschartres protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT marcfadel protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT adrienleguillou protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT remivalter protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT mariedeguigne protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT marionlegeay protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT chloebruneau protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT gaelleroux protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT gaelleroux protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT alexisdescatha protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology AT alexisdescatha protocolfortheuseofcasereportsstudiesandcaseseriesinsystematicreviewsforclinicaltoxicology |
_version_ |
1717780092306849792 |
spelling |
doaj-c3113414e14d4d27a491496072bd089d2021-09-06T04:38:56ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2021-09-01810.3389/fmed.2021.708380708380A Protocol for the Use of Case Reports/Studies and Case Series in Systematic Reviews for Clinical ToxicologyAboubakari Nambiema0Grace Sembajwe1Juleen Lam2Tracey Woodruff3Daniele Mandrioli4Nicholas Chartres5Marc Fadel6Adrien Le Guillou7Remi Valter8Marie Deguigne9Marion Legeay10Chloe Bruneau11Gaël Le Roux12Gaël Le Roux13Alexis Descatha14Alexis Descatha15Univ Angers, CHU Angers, Univ Rennes, INSERM, EHESP, Institut de Recherche en Santé, Environnement et Travail-UMR_S 1085, Angers, FranceDepartment of Occupational Medicine, Epidemiology and Prevention, Donald and Barbara Zucker School of Medicine, Northwell Health, Feinstein Institutes for Medical Research, Hofstra University, Great Neck, NY, United StatesDepartment of Health Sciences, University of California, San Francisco and California State University, Hayward, CA, United StatesProgram on Reproductive Health and the Environment, University of California, San Francisco, San Francisco, CA, United StatesCesare Maltoni Cancer Research Center, Ramazzini Institute, Bologna, ItalyProgram on Reproductive Health and the Environment, University of California, San Francisco, San Francisco, CA, United StatesUniv Angers, CHU Angers, Univ Rennes, INSERM, EHESP, Institut de Recherche en Santé, Environnement et Travail-UMR_S 1085, Angers, FranceDepartment of Research and Public Health, Reims Teaching Hospitals, Robert Debré Hospital, Reims, FranceUniv Angers, CHU Angers, Univ Rennes, INSERM, EHESP, Institut de Recherche en Santé, Environnement et Travail-UMR_S 1085, Angers, FranceCHU Angers, Univ Angers, Poisoning Control Center, Clinical Data Center, Angers, FranceCHU Angers, Univ Angers, Poisoning Control Center, Clinical Data Center, Angers, FranceCHU Angers, Univ Angers, Poisoning Control Center, Clinical Data Center, Angers, FranceUniv Angers, CHU Angers, Univ Rennes, INSERM, EHESP, Institut de Recherche en Santé, Environnement et Travail-UMR_S 1085, Angers, FranceCHU Angers, Univ Angers, Poisoning Control Center, Clinical Data Center, Angers, FranceUniv Angers, CHU Angers, Univ Rennes, INSERM, EHESP, Institut de Recherche en Santé, Environnement et Travail-UMR_S 1085, Angers, FranceCHU Angers, Univ Angers, Poisoning Control Center, Clinical Data Center, Angers, FranceIntroduction: Systematic reviews are routinely used to synthesize current science and evaluate the evidential strength and quality of resulting recommendations. For specific events, such as rare acute poisonings or preliminary reports of new drugs, we posit that case reports/studies and case series (human subjects research with no control group) may provide important evidence for systematic reviews. Our aim, therefore, is to present a protocol that uses rigorous selection criteria, to distinguish high quality case reports/studies and case series for inclusion in systematic reviews.Methods: This protocol will adapt the existing Navigation Guide methodology for specific inclusion of case studies. The usual procedure for systematic reviews will be followed. Case reports/studies and case series will be specified in the search strategy and included in separate sections. Data from these sources will be extracted and where possible, quantitatively synthesized. Criteria for integrating cases reports/studies and case series into the overall body of evidence are that these studies will need to be well-documented, scientifically rigorous, and follow ethical practices. The instructions and standards for evaluating risk of bias will be based on the Navigation Guide. The risk of bias, quality of evidence and the strength of recommendations will be assessed by two independent review teams that are blinded to each other.Conclusion: This is a protocol specified for systematic reviews that use case reports/studies and case series to evaluate the quality of evidence and strength of recommendations in disciplines like clinical toxicology, where case reports/studies are the norm.https://www.frontiersin.org/articles/10.3389/fmed.2021.708380/fulltoxicologyepidemiologypublic healthprotocolsystematic reviewcase reports/studies |