Litchi–associated Acute Encephalitis in Children, Northern Vietnam, 2004–2009
Since the end of the 1990s, unexplained outbreaks of acute encephalitis in children coinciding with litchi harvesting (May–July) have been documented in the Bac Giang Province in northern Vietnam. A retrospective ecologic analysis of data for 2004–2009 involving environmental, agronomic, and climati...
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Centers for Disease Control and Prevention
2012-11-01
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doaj-c32446927d954e3ca551b41fa49db6602020-11-25T00:38:19ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592012-11-0118111817182410.3201/eid1811.111761Litchi–associated Acute Encephalitis in Children, Northern Vietnam, 2004–2009Juliette PaireauNguyen Hai TuanRémi LefrançoisMatthew R. BuckwalterNgu Duy NghiaNguyen Tran HienOlivier LortholarySylvain PoiréeJean-Claude ManuguerraAntoine GessainMatthew L. AlbertPaul T. BreyPhan Thi NgaArnaud FontanetSince the end of the 1990s, unexplained outbreaks of acute encephalitis in children coinciding with litchi harvesting (May–July) have been documented in the Bac Giang Province in northern Vietnam. A retrospective ecologic analysis of data for 2004–2009 involving environmental, agronomic, and climatic factors was conducted to investigate the suspected association between the outbreaks and litchi harvesting. The clinical, biological, and immunologic characteristics of the patients suggested a viral etiology. The ecologic study revealed an independent association between litchi plantation surface proportion and acute encephalitis incidence: Incidence rate ratios were 1.52 (95% CI 0.90–2.57), 2.94 (95% CI 1.88–4.60), and 2.76 (95% CI 1.76–4.32) for second, third, and fourth quartiles, respectively, compared with the lowest quartile. This ecologic study confirmed the suspected association between incidence of acute encephalitis and litchi plantations and should be followed by other studies to identify the causative agent for this syndrome.https://wwwnc.cdc.gov/eid/article/18/11/11-1761_articleEncephalitisepidemicsdisease outbreaksepidemiologyrisk factorslitchi |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Juliette Paireau Nguyen Hai Tuan Rémi Lefrançois Matthew R. Buckwalter Ngu Duy Nghia Nguyen Tran Hien Olivier Lortholary Sylvain Poirée Jean-Claude Manuguerra Antoine Gessain Matthew L. Albert Paul T. Brey Phan Thi Nga Arnaud Fontanet |
spellingShingle |
Juliette Paireau Nguyen Hai Tuan Rémi Lefrançois Matthew R. Buckwalter Ngu Duy Nghia Nguyen Tran Hien Olivier Lortholary Sylvain Poirée Jean-Claude Manuguerra Antoine Gessain Matthew L. Albert Paul T. Brey Phan Thi Nga Arnaud Fontanet Litchi–associated Acute Encephalitis in Children, Northern Vietnam, 2004–2009 Emerging Infectious Diseases Encephalitis epidemics disease outbreaks epidemiology risk factors litchi |
author_facet |
Juliette Paireau Nguyen Hai Tuan Rémi Lefrançois Matthew R. Buckwalter Ngu Duy Nghia Nguyen Tran Hien Olivier Lortholary Sylvain Poirée Jean-Claude Manuguerra Antoine Gessain Matthew L. Albert Paul T. Brey Phan Thi Nga Arnaud Fontanet |
author_sort |
Juliette Paireau |
title |
Litchi–associated Acute Encephalitis in Children, Northern Vietnam, 2004–2009 |
title_short |
Litchi–associated Acute Encephalitis in Children, Northern Vietnam, 2004–2009 |
title_full |
Litchi–associated Acute Encephalitis in Children, Northern Vietnam, 2004–2009 |
title_fullStr |
Litchi–associated Acute Encephalitis in Children, Northern Vietnam, 2004–2009 |
title_full_unstemmed |
Litchi–associated Acute Encephalitis in Children, Northern Vietnam, 2004–2009 |
title_sort |
litchi–associated acute encephalitis in children, northern vietnam, 2004–2009 |
publisher |
Centers for Disease Control and Prevention |
series |
Emerging Infectious Diseases |
issn |
1080-6040 1080-6059 |
publishDate |
2012-11-01 |
description |
Since the end of the 1990s, unexplained outbreaks of acute encephalitis in children coinciding with litchi harvesting (May–July) have been documented in the Bac Giang Province in northern Vietnam. A retrospective ecologic analysis of data for 2004–2009 involving environmental, agronomic, and climatic factors was conducted to investigate the suspected association between the outbreaks and litchi harvesting. The clinical, biological, and immunologic characteristics of the patients suggested a viral etiology. The ecologic study revealed an independent association between litchi plantation surface proportion and acute encephalitis incidence: Incidence rate ratios were 1.52 (95% CI 0.90–2.57), 2.94 (95% CI 1.88–4.60), and 2.76 (95% CI 1.76–4.32) for second, third, and fourth quartiles, respectively, compared with the lowest quartile. This ecologic study confirmed the suspected association between incidence of acute encephalitis and litchi plantations and should be followed by other studies to identify the causative agent for this syndrome. |
topic |
Encephalitis epidemics disease outbreaks epidemiology risk factors litchi |
url |
https://wwwnc.cdc.gov/eid/article/18/11/11-1761_article |
work_keys_str_mv |
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