Gene regulatory network inference from multifactorial perturbation data using both regression and correlation analyses.

An important problem in systems biology is to reconstruct gene regulatory networks (GRNs) from experimental data and other a priori information. The DREAM project offers some types of experimental data, such as knockout data, knockdown data, time series data, etc. Among them, multifactorial perturba...

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Bibliographic Details
Main Authors: Jie Xiong, Tong Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3448649?pdf=render