A subset of conserved mammalian long non-coding RNAs are fossils of ancestral protein-coding genes

A subset of conserved mammalian long non-coding RNAs are fossils of ancestral protein-coding genes

Abstract Background Only a small portion of human long non-coding RNAs (lncRNAs) appear to be conserved outside of mammals, but the events underlying the birth of new lncRNAs in mammals remain largely unknown. One potential source is remnants of protein-coding genes that transitioned into lncRNAs. R...

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Bibliographic Details
Main Authors: Hadas Hezroni, Rotem Ben-Tov Perry, Zohar Meir, Gali Housman, Yoav Lubelsky, Igor Ulitsky
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Genome Biology
Subjects:
Long noncoding RNAs
Evolution
Pseudogenes
Translational regulation
uORFs
X inactivation
Online Access:http://link.springer.com/article/10.1186/s13059-017-1293-0

Internet

http://link.springer.com/article/10.1186/s13059-017-1293-0

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