Tumor Nonimmune-Microenvironment-Related Gene Expression Signature Predicts Brain Metastasis in Lung Adenocarcinoma Patients after Surgery: A Machine Learning Approach Using Gene Expression Profiling

Tumor Nonimmune-Microenvironment-Related Gene Expression Signature Predicts Brain Metastasis in Lung Adenocarcinoma Patients after Surgery: A Machine Learning Approach Using Gene Expression Profiling

Using a machine learning approach with a gene expression profile, we discovered a tumor nonimmune-microenvironment-related gene expression signature, including extracellular matrix (ECM) remodeling, epithelial–mesenchymal transition (EMT), and angiogenesis, that could predict brain metastasis (BM) a...

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Bibliographic Details
Main Authors: Seokjin Haam, Jae-Ho Han, Hyun Woo Lee, Young Wha Koh
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
lung adenocarcinoma
brain metastasis
gene expression profile
tumor nonimmune microenvironment
extracellular matrix
machine learning
Online Access:https://www.mdpi.com/2072-6694/13/17/4468

Internet

https://www.mdpi.com/2072-6694/13/17/4468

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