Seroprevalence of Toxoplasma gondii antibodies and associated risk factors among children in Shandong and Jilin provinces, China
Objective: Infection by the protozoan parasite Toxoplasma gondii is generally prevalent in animals and humans worldwide. However, little is known about T. gondii infection among children in China. Thus, the present study was conducted to detect the seroprevalence of T. gondii infection and estimate...
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doaj-c3578543511f420885c98cc4969a3d262020-11-25T01:00:19ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112015-01-0130C333510.1016/j.ijid.2014.11.002Seroprevalence of Toxoplasma gondii antibodies and associated risk factors among children in Shandong and Jilin provinces, ChinaQing-Feng Meng0Hai-Long You1Na Zhou2Wei Dong3Wei-Lin Wang4Wei-Li Wang5Wei Cong6Jilin Entry-Exit Inspection and Quarantine Bureau, Changchun, Jilin Province 130062, PR ChinaFirst Hospital of Jilin University, Changchun, Jilin Province 130000, PR ChinaAffilliated Hospital of Medical College, Qingdao University, Qingdao, Shandong Province 266000, PR ChinaWeihaiwei People's Hospital, Weihai, Shandong Province 264200, PR ChinaJilin Entry-Exit Inspection and Quarantine Bureau, Changchun, Jilin Province 130062, PR ChinaJilin Entry-Exit Inspection and Quarantine Bureau, Changchun, Jilin Province 130062, PR ChinaCollege of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin Province 130118, PR ChinaObjective: Infection by the protozoan parasite Toxoplasma gondii is generally prevalent in animals and humans worldwide. However, little is known about T. gondii infection among children in China. Thus, the present study was conducted to detect the seroprevalence of T. gondii infection and estimate associated risk factors among children in eastern China. Methods: A cross-sectional study of 1500 children from three cities (Changchun, Qingdao, Weihai) was conducted between May 2013 and July 2014 to estimate the seroprevalence and potential risk factors associated with acquiring T. gondii infection in children in China. Demographic and blood samples were collected, and anti-T. gondii IgG and IgM antibodies were measured by ELISA. Results: The mean age of the 1500 children participating in the study was 9.03 years (range 1-18). The overall seroprevalence of Toxoplasma infection was 15.13%, of which 13.13% were positive for only anti-Toxoplasma IgG antibodies, 3.13% were positive for both anti-Toxoplasma IgG and IgM antibodies and 2.00% were IgM positive and IgG negative. Moreover, raising cats at home (OR=1.94, 95% CI=1.288-2.912, P=0.002) and hand washing habits (OR=0.38, 95% CI=0.230-0.635, P<0.001) were estimated to be risk and protective factors associated with Toxoplasma seroprevalence, respectively. Conclusions: The present study revealed for the first time that children's infection with T. gondii is common in eastern China. The present data indicate a need to implement methods of prevention and control measures against Toxoplasma infection in China.http://www.sciencedirect.com/science/article/pii/S1201971214016774Toxoplasma gondiichildrenseroprevalencerisk factorsChina |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Qing-Feng Meng Hai-Long You Na Zhou Wei Dong Wei-Lin Wang Wei-Li Wang Wei Cong |
spellingShingle |
Qing-Feng Meng Hai-Long You Na Zhou Wei Dong Wei-Lin Wang Wei-Li Wang Wei Cong Seroprevalence of Toxoplasma gondii antibodies and associated risk factors among children in Shandong and Jilin provinces, China International Journal of Infectious Diseases Toxoplasma gondii children seroprevalence risk factors China |
author_facet |
Qing-Feng Meng Hai-Long You Na Zhou Wei Dong Wei-Lin Wang Wei-Li Wang Wei Cong |
author_sort |
Qing-Feng Meng |
title |
Seroprevalence of Toxoplasma gondii antibodies and associated risk factors among children in Shandong and Jilin provinces, China |
title_short |
Seroprevalence of Toxoplasma gondii antibodies and associated risk factors among children in Shandong and Jilin provinces, China |
title_full |
Seroprevalence of Toxoplasma gondii antibodies and associated risk factors among children in Shandong and Jilin provinces, China |
title_fullStr |
Seroprevalence of Toxoplasma gondii antibodies and associated risk factors among children in Shandong and Jilin provinces, China |
title_full_unstemmed |
Seroprevalence of Toxoplasma gondii antibodies and associated risk factors among children in Shandong and Jilin provinces, China |
title_sort |
seroprevalence of toxoplasma gondii antibodies and associated risk factors among children in shandong and jilin provinces, china |
publisher |
Elsevier |
series |
International Journal of Infectious Diseases |
issn |
1201-9712 1878-3511 |
publishDate |
2015-01-01 |
description |
Objective: Infection by the protozoan parasite Toxoplasma gondii is generally prevalent in animals and humans worldwide. However, little is known about T. gondii infection among children in China. Thus, the present study was conducted to detect the seroprevalence of T. gondii infection and estimate associated risk factors among children in eastern China.
Methods: A cross-sectional study of 1500 children from three cities (Changchun, Qingdao, Weihai) was conducted between May 2013 and July 2014 to estimate the seroprevalence and potential risk factors associated with acquiring T. gondii infection in children in China. Demographic and blood samples were collected, and anti-T. gondii IgG and IgM antibodies were measured by ELISA.
Results: The mean age of the 1500 children participating in the study was 9.03 years (range 1-18). The overall seroprevalence of Toxoplasma infection was 15.13%, of which 13.13% were positive for only anti-Toxoplasma IgG antibodies, 3.13% were positive for both anti-Toxoplasma IgG and IgM antibodies and 2.00% were IgM positive and IgG negative. Moreover, raising cats at home (OR=1.94, 95% CI=1.288-2.912, P=0.002) and hand washing habits (OR=0.38, 95% CI=0.230-0.635, P<0.001) were estimated to be risk and protective factors associated with Toxoplasma seroprevalence, respectively.
Conclusions: The present study revealed for the first time that children's infection with T. gondii is common in eastern China. The present data indicate a need to implement methods of prevention and control measures against Toxoplasma infection in China. |
topic |
Toxoplasma gondii children seroprevalence risk factors China |
url |
http://www.sciencedirect.com/science/article/pii/S1201971214016774 |
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