Effect of vitrectomy combined medication hyperplastic on patients with diabetic retinopathy
AIM: To observe the comparison of vitrectomy combined drug therapy(Ranibizumab injection)and single vitrectomy for proliferatived diabetic retinopathy(PDR)and the influence of the curative effect and prognosis of patients. <p>METHODS: In this study, 112 cases(125 eyes)with PDR were selected an...
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doaj-c3869ff91f494125bf38dce5f338477f2020-11-24T22:47:54ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-08-011581402140410.3980/j.issn.1672-5123.2015.8.25Effect of vitrectomy combined medication hyperplastic on patients with diabetic retinopathyXue-Qun Yu0Guo-Ping Cao1Ming-Xia Tang2Department of Ophthalmology, Taizhou People's Hospital, Taizhou 225300, Jiangsu Province, ChinaDepartment of Ophthalmology, Taizhou People's Hospital, Taizhou 225300, Jiangsu Province, ChinaDepartment of Ophthalmology, Taizhou People's Hospital, Taizhou 225300, Jiangsu Province, ChinaAIM: To observe the comparison of vitrectomy combined drug therapy(Ranibizumab injection)and single vitrectomy for proliferatived diabetic retinopathy(PDR)and the influence of the curative effect and prognosis of patients. <p>METHODS: In this study, 112 cases(125 eyes)with PDR were selected and randomly divided into experimental group and control group(<i>n</i>=56). Fifty-six cases(61 eyes)in experimental group were injected by drug therapy of 0.5mg ranibizumab and received vitrectomy; In control group, 56 cases(64 eyes)were received single vitrectomy. The intraoperative and postoperative differences of clinical indicators were analyzed in two groups. <p>RESULTS: The average operation time, intraoperative electric coagulation hemostasis rate and iatrogenic hiatal incidence of the experimental group were lower than that of the control group:(95.00±13.00)min <i>vs</i>(133.00±14.5)min, 11% <i>vs</i> 34%, 5% <i>vs</i> 20%, respectively(<i>P</i><0.05). The anterior chamber and vitreous body cavity hemorrhage rate within postoperative 1mo in the experimental group were lower than that of the control group: 7% <i>vs</i> 23%, 5% <i>vs</i> 12%, respectively(<i>P</i><0.05). The postoperative visual acuity of experimental group was better than that of the control group: 0.375±0.210 <i>vs </i>0.261±0.170, respectively(<i>P</i><0.05). <p>CONCLUSION: Patients with PDR injected with ranibizumab in vitreous cavity before vitrectomy can effectively reduce the operation time, less intraoperative blood loss, the incidence of iatrogenic hiatus, and intraoperative and postoperative complications. The postoperative visual acuity was better than before.http://ies.ijo.cn/cn_publish/2015/8/201508025.pdfvitrectomyproliferatived diabetic retinopathyranibizumab |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xue-Qun Yu Guo-Ping Cao Ming-Xia Tang |
spellingShingle |
Xue-Qun Yu Guo-Ping Cao Ming-Xia Tang Effect of vitrectomy combined medication hyperplastic on patients with diabetic retinopathy Guoji Yanke Zazhi vitrectomy proliferatived diabetic retinopathy ranibizumab |
author_facet |
Xue-Qun Yu Guo-Ping Cao Ming-Xia Tang |
author_sort |
Xue-Qun Yu |
title |
Effect of vitrectomy combined medication hyperplastic on patients with diabetic retinopathy |
title_short |
Effect of vitrectomy combined medication hyperplastic on patients with diabetic retinopathy |
title_full |
Effect of vitrectomy combined medication hyperplastic on patients with diabetic retinopathy |
title_fullStr |
Effect of vitrectomy combined medication hyperplastic on patients with diabetic retinopathy |
title_full_unstemmed |
Effect of vitrectomy combined medication hyperplastic on patients with diabetic retinopathy |
title_sort |
effect of vitrectomy combined medication hyperplastic on patients with diabetic retinopathy |
publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
series |
Guoji Yanke Zazhi |
issn |
1672-5123 1672-5123 |
publishDate |
2015-08-01 |
description |
AIM: To observe the comparison of vitrectomy combined drug therapy(Ranibizumab injection)and single vitrectomy for proliferatived diabetic retinopathy(PDR)and the influence of the curative effect and prognosis of patients. <p>METHODS: In this study, 112 cases(125 eyes)with PDR were selected and randomly divided into experimental group and control group(<i>n</i>=56). Fifty-six cases(61 eyes)in experimental group were injected by drug therapy of 0.5mg ranibizumab and received vitrectomy; In control group, 56 cases(64 eyes)were received single vitrectomy. The intraoperative and postoperative differences of clinical indicators were analyzed in two groups. <p>RESULTS: The average operation time, intraoperative electric coagulation hemostasis rate and iatrogenic hiatal incidence of the experimental group were lower than that of the control group:(95.00±13.00)min <i>vs</i>(133.00±14.5)min, 11% <i>vs</i> 34%, 5% <i>vs</i> 20%, respectively(<i>P</i><0.05). The anterior chamber and vitreous body cavity hemorrhage rate within postoperative 1mo in the experimental group were lower than that of the control group: 7% <i>vs</i> 23%, 5% <i>vs</i> 12%, respectively(<i>P</i><0.05). The postoperative visual acuity of experimental group was better than that of the control group: 0.375±0.210 <i>vs </i>0.261±0.170, respectively(<i>P</i><0.05). <p>CONCLUSION: Patients with PDR injected with ranibizumab in vitreous cavity before vitrectomy can effectively reduce the operation time, less intraoperative blood loss, the incidence of iatrogenic hiatus, and intraoperative and postoperative complications. The postoperative visual acuity was better than before. |
topic |
vitrectomy proliferatived diabetic retinopathy ranibizumab |
url |
http://ies.ijo.cn/cn_publish/2015/8/201508025.pdf |
work_keys_str_mv |
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