Membrane Drug Transporters and Chemoresistance in Human Pancreatic Carcinoma

Membrane Drug Transporters and Chemoresistance in Human Pancreatic Carcinoma

Pancreatic cancer ranks among the tumors most resistant to chemotherapy. Such chemoresistance of tumors can be mediated by various cellular mechanisms including dysregulated apoptosis or ineffective drug concentration at the intracellular target sites. In this review, we highlight recent advances in...

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Bibliographic Details
Main Authors:	Ralf Jesnowski, Martina Schnölzer, Matthias Löhr, Wolfgang Hagmann, Ralf Faissner
Format:	Article
Language:	English
Published:	MDPI AG 2010-12-01
Series:	Cancers
Subjects:	ABC transporters chemoresistance pancreatic cancer gemcitabine 5-fluorouracil multidrug resistance proteins S100A4 OATPs nucleoside transporters RNA interference
Online Access:	http://www.mdpi.com/2072-6694/3/1/106/

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