Generation of a human iPSC line from a patient with an optic atrophy ‘plus’ phenotype due to a mutation in the OPA1 gene
Human iPSC line Oex2054SV.4 was generated from fibroblasts of a patient with an optic atrophy ‘plus’ phenotype associated with a heterozygous mutation in the OPA1 gene. Reprogramming factors OCT3/4, SOX2, CMYC and KLF4 were delivered using a non-integrative methodology that involves the use of Senda...
Main Authors: | Teresa Galera-Monge, Francisco Zurita-Díaz, Ana Moreno-Izquierdo, Mario F. Fraga, Agustin F. Fernández, C. Ayuso, Rafael Garesse, M. Esther Gallardo |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2016-05-01
|
Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506116300095 |
Similar Items
-
Establishment of a human DOA 'plus' iPSC line, IISHDOi003-A, with the mutation in the OPA1 gene: c.1635C>A; p.Ser545Arg
by: Francisco Zurita-Díaz, et al.
Published: (2017-10-01) -
Generation of a human iPSC line from a patient with Leigh syndrome caused by a mutation in the MT-ATP6 gene
by: Teresa Galera-Monge, et al.
Published: (2016-05-01) -
Generation of a human iPSC line, IISHDOi002-A, with a 46, XY/47, XYY mosaicism and belonging to an African mitochondrial haplogroup
by: María del Carmen Ortuño-Costela, et al.
Published: (2018-04-01) -
Establishment of a human iPSC line (IISHDOi001-A) from a patient with McArdle disease
by: María del Carmen Ortuño-Costela, et al.
Published: (2017-08-01) -
Establishment of a human iPSC line, IISHDOi004-A, from a patient with Usher syndrome associated with the mutation c.2276G>T; p.Cys759Phe in the USH2A gene
by: Francisco Zurita-Díaz, et al.
Published: (2018-08-01)