Restriction Endonuclease-Based Assays for DNA Detection and Isothermal Exponential Signal Amplification

Restriction Endonuclease-Based Assays for DNA Detection and Isothermal Exponential Signal Amplification

Application of restriction endonuclease (REase) enzymes for specific detection of nucleic acids provides for high assay specificity, convenience and low cost. A direct restriction assay format is based on the specific enzymatic cleavage of a target–probe hybrid that is accompanied with the release o...

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Bibliographic Details
Main Authors: Maria Smith, Kenneth Smith, Alan Olstein, Andrew Oleinikov, Andrey Ghindilis
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Sensors
Subjects:
DNA assay
nucleic acid
isothermal
signal amplification
restriction endonuclease
Online Access:https://www.mdpi.com/1424-8220/20/14/3873

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