Specific Inhibition of HIF Activity: Can Peptides Lead the Way?
Reduced oxygen availability (hypoxia) is a characteristic of many disorders including cancer. Central components of the systemic and cellular response to hypoxia are the Hypoxia Inducible Factors (HIFs), a small family of heterodimeric transcription factors that directly or indirectly regulate the e...
Main Authors: | Ilias Mylonis, Georgia Chachami, George Simos |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/3/410 |
Similar Items
-
The Role of Sumoylation in the Response to Hypoxia: An Overview
by: Chrysa Filippopoulou, et al.
Published: (2020-10-01) -
Ways into Understanding HIF Inhibition
by: Tina Schönberger, et al.
Published: (2021-01-01) -
Hypoxia-Inducible Factors and the Regulation of Lipid Metabolism
by: Ilias Mylonis, et al.
Published: (2019-03-01) -
Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells
by: Peter A.C. Wing, et al.
Published: (2021-04-01) -
Hypoxia Inducible Factor-1α (HIF-1 α) and its Role in Tumour Progression to Malignancy
by: Gaurav Mrinal Sharma
Published: (2008-07-01)