Epigenetic Priming in Childhood Acute Lymphoblastic Leukemia

Epigenetic Priming in Childhood Acute Lymphoblastic Leukemia

Leukemogenesis is considered to be a process by which a normal cell acquires new but aberrant identity in order to disseminate a malignant clonal population. Under this setting, the phenotype of the leukemic cells is identical to the leukemia-initiating cell in which the genetic insult is taking pla...

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Bibliographic Details
Main Authors: Javier Raboso-Gallego, Ana Casado-García, Marta Isidro-Hernández, Carolina Vicente-Dueñas
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
epigenetic priming
reprogramming
childhood leukemia
B-ALL
T-ALL
stem cells
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00137/full

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