Prevalence and correlates of frailty in an older rural African population: findings from the HAALSI cohort study
Abstract Background Frailty is a key predictor of death and dependency, yet little is known about frailty in sub-Saharan Africa despite rapid population ageing. We describe the prevalence and correlates of phenotypic frailty using data from the Health and Aging in Africa: Longitudinal Studies of an...
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doaj-c3e880a1dc104c6880c6bccb8e6826eb2020-11-25T03:42:47ZengBMCBMC Geriatrics1471-23182017-12-0117111010.1186/s12877-017-0694-yPrevalence and correlates of frailty in an older rural African population: findings from the HAALSI cohort studyCollin F. Payne0Alisha Wade1Chodziwadziwa W. Kabudula2Justine I. Davies3Angela Y. Chang4F. Xavier Gomez-Olive5Kathleen Kahn6Lisa F. Berkman7Stephen M. Tollman8Joshua A. Salomon9Miles D. Witham10Center for Population and Development Studies, Harvard UniversityMedical Research Council/Wits University Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of Health Sciences, University of the WitwatersrandMedical Research Council/Wits University Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of Health Sciences, University of the WitwatersrandMedical Research Council/Wits University Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of Health Sciences, University of the WitwatersrandDepartment of Global Health and Population, Harvard T.H. Chan School of Public HealthCenter for Population and Development Studies, Harvard UniversityMedical Research Council/Wits University Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of Health Sciences, University of the WitwatersrandCenter for Population and Development Studies, Harvard UniversityMedical Research Council/Wits University Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of Health Sciences, University of the WitwatersrandDepartment of Global Health and Population, Harvard T.H. Chan School of Public HealthMedical Research Council/Wits University Rural Public Health and Health Transitions Research Unit, School of Public Health, Faculty of Health Sciences, University of the WitwatersrandAbstract Background Frailty is a key predictor of death and dependency, yet little is known about frailty in sub-Saharan Africa despite rapid population ageing. We describe the prevalence and correlates of phenotypic frailty using data from the Health and Aging in Africa: Longitudinal Studies of an INDEPTH Community cohort. Methods We analysed data from rural South Africans aged 40 and over. We used low grip strength, slow gait speed, low body mass index, and combinations of self-reported exhaustion, decline in health, low physical activity and high self-reported sedentariness to derive nine variants of a phenotypic frailty score. Each frailty category was compared with self-reported health, subjective wellbeing, impairment in activities of daily living and the presence of multimorbidity. Cox regression analyses were used to compare subsequent all-cause mortality for non-frail (score 0), pre-frail (score 1–2) and frail participants (score 3+). Results Five thousand fifty nine individuals (mean age 61.7 years, 2714 female) were included in the analyses. The nine frailty score variants yielded a range of frailty prevalences (5.4% to 13.2%). For all variants, rates were higher in women than in men, and rose steeply with age. Frailty was associated with worse subjective wellbeing, and worse self-reported health. Both prefrailty and frailty were associated with a higher risk of death during a mean 17 month follow up for all score variants (hazard ratios 1.29 to 2.41 for pre-frail vs non-frail; hazard ratios 2.65 to 8.91 for frail vs non-frail). Conclusions Phenotypic frailty could be measured in this older South African population, and was associated with worse health, wellbeing and earlier death.http://link.springer.com/article/10.1186/s12877-017-0694-yFried frailty scoreMortalityMultimorbidityActivities of daily livingRural South Africa |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Collin F. Payne Alisha Wade Chodziwadziwa W. Kabudula Justine I. Davies Angela Y. Chang F. Xavier Gomez-Olive Kathleen Kahn Lisa F. Berkman Stephen M. Tollman Joshua A. Salomon Miles D. Witham |
spellingShingle |
Collin F. Payne Alisha Wade Chodziwadziwa W. Kabudula Justine I. Davies Angela Y. Chang F. Xavier Gomez-Olive Kathleen Kahn Lisa F. Berkman Stephen M. Tollman Joshua A. Salomon Miles D. Witham Prevalence and correlates of frailty in an older rural African population: findings from the HAALSI cohort study BMC Geriatrics Fried frailty score Mortality Multimorbidity Activities of daily living Rural South Africa |
author_facet |
Collin F. Payne Alisha Wade Chodziwadziwa W. Kabudula Justine I. Davies Angela Y. Chang F. Xavier Gomez-Olive Kathleen Kahn Lisa F. Berkman Stephen M. Tollman Joshua A. Salomon Miles D. Witham |
author_sort |
Collin F. Payne |
title |
Prevalence and correlates of frailty in an older rural African population: findings from the HAALSI cohort study |
title_short |
Prevalence and correlates of frailty in an older rural African population: findings from the HAALSI cohort study |
title_full |
Prevalence and correlates of frailty in an older rural African population: findings from the HAALSI cohort study |
title_fullStr |
Prevalence and correlates of frailty in an older rural African population: findings from the HAALSI cohort study |
title_full_unstemmed |
Prevalence and correlates of frailty in an older rural African population: findings from the HAALSI cohort study |
title_sort |
prevalence and correlates of frailty in an older rural african population: findings from the haalsi cohort study |
publisher |
BMC |
series |
BMC Geriatrics |
issn |
1471-2318 |
publishDate |
2017-12-01 |
description |
Abstract Background Frailty is a key predictor of death and dependency, yet little is known about frailty in sub-Saharan Africa despite rapid population ageing. We describe the prevalence and correlates of phenotypic frailty using data from the Health and Aging in Africa: Longitudinal Studies of an INDEPTH Community cohort. Methods We analysed data from rural South Africans aged 40 and over. We used low grip strength, slow gait speed, low body mass index, and combinations of self-reported exhaustion, decline in health, low physical activity and high self-reported sedentariness to derive nine variants of a phenotypic frailty score. Each frailty category was compared with self-reported health, subjective wellbeing, impairment in activities of daily living and the presence of multimorbidity. Cox regression analyses were used to compare subsequent all-cause mortality for non-frail (score 0), pre-frail (score 1–2) and frail participants (score 3+). Results Five thousand fifty nine individuals (mean age 61.7 years, 2714 female) were included in the analyses. The nine frailty score variants yielded a range of frailty prevalences (5.4% to 13.2%). For all variants, rates were higher in women than in men, and rose steeply with age. Frailty was associated with worse subjective wellbeing, and worse self-reported health. Both prefrailty and frailty were associated with a higher risk of death during a mean 17 month follow up for all score variants (hazard ratios 1.29 to 2.41 for pre-frail vs non-frail; hazard ratios 2.65 to 8.91 for frail vs non-frail). Conclusions Phenotypic frailty could be measured in this older South African population, and was associated with worse health, wellbeing and earlier death. |
topic |
Fried frailty score Mortality Multimorbidity Activities of daily living Rural South Africa |
url |
http://link.springer.com/article/10.1186/s12877-017-0694-y |
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