Cellular Nutrition in Complex Three-Dimensional Scaffolds: A Comparison between Experiments and Computer Simulations

Cellular Nutrition in Complex Three-Dimensional Scaffolds: A Comparison between Experiments and Computer Simulations

Studies on bone cell ingrowth into synthetic, porous three-dimensional (3D) implants showed difficulties arising from impaired cellular proliferation and differentiation in the core region of these scaffolds with increasing scaffold volume in vitro. Therefore, we developed an in vitro perfusion cell...

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Bibliographic Details
Main Authors: Claudia Bergemann, Patrick Elter, Regina Lange, Volker Weißmann, Harald Hansmann, Ernst-Dieter Klinkenberg, Barbara Nebe
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2015/584362

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