Prediction and testing of biological networks underlying intestinal cancer.

Colorectal cancer progresses through an accumulation of somatic mutations, some of which reside in so-called "driver" genes that provide a growth advantage to the tumor. To identify points of intersection between driver gene pathways, we implemented a network analysis framework using prote...

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Bibliographic Details
Main Authors: Vishal N Patel, Gurkan Bebek, John M Mariadason, Donghai Wang, Leonard H Augenlicht, Mark R Chance
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2931697?pdf=render

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