Identification of the protein kinases Pyk3 and Phg2 as regulators of the STATc-mediated response to hyperosmolarity.
Cellular adaptation to changes in environmental osmolarity is crucial for cell survival. In Dictyostelium, STATc is a key regulator of the transcriptional response to hyperosmotic stress. Its phosphorylation and consequent activation is controlled by two signaling branches, one cGMP- and the other C...
Main Authors: | Linh Hai Vu, Tsuyoshi Araki, Jianbo Na, Christoph S Clemen, Jeffrey G Williams, Ludwig Eichinger |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3934975?pdf=render |
Similar Items
-
STATc is a key regulator of the transcriptional response to hyperosmotic shock
by: Eichinger Ludwig, et al.
Published: (2007-05-01) -
The related kinases FAK and Pyk2 serve distinct functions in TCR-mediated T cell activation
by: Chapman, Nicole
Published: (2013) -
Signal Transduction by Proline-Rich Tyrosine Kinase Pyk2
by: Dikic, Inga
Published: (2002) -
The production of antihypertensive peptides with genetical engineered Bacillus subtilis (pHG)
by: Hui-Chu Huang, et al.
Published: (2005) -
Pyruvate Kinase M2 Contributes to TLR-Mediated Inflammation and Autoimmunity by Promoting Pyk2 Activation
by: Xin Zhang, et al.
Published: (2021-05-01)