Polyphosphate kinase from M. tuberculosis: an interconnect between the genetic and biochemical role.

Polyphosphate kinase from M. tuberculosis: an interconnect between the genetic and biochemical role.

The enzyme Polyphosphate Kinase (PPK) catalyses the reversible transfer of the terminal γ-Pi of ATP to form a long chain Polyphosphate (PolyP). Using an IPTG inducible mycobacterial vector, the vulnerability of this gene has been evaluated by antisense knockdown experiments in M. tuberculosis. Expre...

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Bibliographic Details
Main Authors: Vijayalakshmi Jagannathan, Parvinder Kaur, Santanu Datta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3002279?pdf=render

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