Design and Synthesis of a Fluorescent Probe Based on Copper Complex for Selective Detection of Hydrogen Sulfide

Design and Synthesis of a Fluorescent Probe Based on Copper Complex for Selective Detection of Hydrogen Sulfide

A novel fluorescence probe NA-LCX was rationally designed and synthesized for the sequential recognition of Cu2+ and H2S by the combination of hydroxyl-naphthalene and diformylphenol groups. The response properties of NA-LCX for Cu2+ ions and H2S with “on-off-on” manner were investigated by fluoresc...

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Main Authors: Guanglan Mao, Chenxi Liu, Nan Yang, Linlin Yang, Guangjie He
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Sensors
Online Access:http://dx.doi.org/10.1155/2021/8822558
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spelling doaj-c43f98ba3e144b4eb104064af765dd232021-03-01T01:14:17ZengHindawi LimitedJournal of Sensors1687-72682021-01-01202110.1155/2021/8822558Design and Synthesis of a Fluorescent Probe Based on Copper Complex for Selective Detection of Hydrogen SulfideGuanglan Mao0Chenxi Liu1Nan Yang2Linlin Yang3Guangjie He4Department of Traditional Chinese MedicineXinxiang Key Laboratory of Forensic Science EvidenceXinxiang Key Laboratory of Forensic Science EvidenceXinxiang Key Laboratory of Forensic Science EvidenceXinxiang Key Laboratory of Forensic Science EvidenceA novel fluorescence probe NA-LCX was rationally designed and synthesized for the sequential recognition of Cu2+ and H2S by the combination of hydroxyl-naphthalene and diformylphenol groups. The response properties of NA-LCX for Cu2+ ions and H2S with “on-off-on” manner were investigated by fluorescence emission spectra. A highly selective and sensitive response of complex NA-LCX-Cu2+ for H2S over other competing amino acids was observed with a limit of detection at 2.79 μM. The stoichiometry of NA-LCX toward Cu2+ ions was determined to be 1 : 1 by the UV-Vis absorption spectrum, and the coordination configuration was calculated by density functional theory (DFT) calculations. Moreover, probe NA-LCX was applied successfully for the recognition of Cu2+ ions and H2S in living cells.http://dx.doi.org/10.1155/2021/8822558
collection DOAJ
language English
format Article
sources DOAJ
author Guanglan Mao
Chenxi Liu
Nan Yang
Linlin Yang
Guangjie He
spellingShingle Guanglan Mao
Chenxi Liu
Nan Yang
Linlin Yang
Guangjie He
Design and Synthesis of a Fluorescent Probe Based on Copper Complex for Selective Detection of Hydrogen Sulfide
Journal of Sensors
author_facet Guanglan Mao
Chenxi Liu
Nan Yang
Linlin Yang
Guangjie He
author_sort Guanglan Mao
title Design and Synthesis of a Fluorescent Probe Based on Copper Complex for Selective Detection of Hydrogen Sulfide
title_short Design and Synthesis of a Fluorescent Probe Based on Copper Complex for Selective Detection of Hydrogen Sulfide
title_full Design and Synthesis of a Fluorescent Probe Based on Copper Complex for Selective Detection of Hydrogen Sulfide
title_fullStr Design and Synthesis of a Fluorescent Probe Based on Copper Complex for Selective Detection of Hydrogen Sulfide
title_full_unstemmed Design and Synthesis of a Fluorescent Probe Based on Copper Complex for Selective Detection of Hydrogen Sulfide
title_sort design and synthesis of a fluorescent probe based on copper complex for selective detection of hydrogen sulfide
publisher Hindawi Limited
series Journal of Sensors
issn 1687-7268
publishDate 2021-01-01
description A novel fluorescence probe NA-LCX was rationally designed and synthesized for the sequential recognition of Cu2+ and H2S by the combination of hydroxyl-naphthalene and diformylphenol groups. The response properties of NA-LCX for Cu2+ ions and H2S with “on-off-on” manner were investigated by fluorescence emission spectra. A highly selective and sensitive response of complex NA-LCX-Cu2+ for H2S over other competing amino acids was observed with a limit of detection at 2.79 μM. The stoichiometry of NA-LCX toward Cu2+ ions was determined to be 1 : 1 by the UV-Vis absorption spectrum, and the coordination configuration was calculated by density functional theory (DFT) calculations. Moreover, probe NA-LCX was applied successfully for the recognition of Cu2+ ions and H2S in living cells.
url http://dx.doi.org/10.1155/2021/8822558
work_keys_str_mv AT guanglanmao designandsynthesisofafluorescentprobebasedoncoppercomplexforselectivedetectionofhydrogensulfide
AT chenxiliu designandsynthesisofafluorescentprobebasedoncoppercomplexforselectivedetectionofhydrogensulfide
AT nanyang designandsynthesisofafluorescentprobebasedoncoppercomplexforselectivedetectionofhydrogensulfide
AT linlinyang designandsynthesisofafluorescentprobebasedoncoppercomplexforselectivedetectionofhydrogensulfide
AT guangjiehe designandsynthesisofafluorescentprobebasedoncoppercomplexforselectivedetectionofhydrogensulfide
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