Antipsychotic Polypharmacy and High Doses in a Rural Portuguese Community Mental Health Service
Introduction: Antipsychotic polypharmacy (APP) and high dose (APHD) remain a common practice in the treatment of severe mental illness, even though they are not supported by current international guidelines. Methods: We aimed to establish the prescribing patterns of antipsychotics in a community...
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Sociedade Portuguesa de Psiquiatria e Saúde Mental
2021-09-01
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doaj-c44bc258bed54ba6bfcf61b605414a2e2021-09-14T18:47:49ZengSociedade Portuguesa de Psiquiatria e Saúde MentalRevista Portuguesa de Psiquiatria e Saúde Mental2184-55222184-54172021-09-017310.51338/rppsm.2021.v7.i3.163Antipsychotic Polypharmacy and High Doses in a Rural Portuguese Community Mental Health ServiceSara Ramos0Diana Cruz1Bianca Jesus2João Correia3Isabel Vaz4João Mendes5Departamento de Psiquiatria e Saúde Mental da Unidade Local de Saúde da Guarda, EPE, Guarda, PortugalDepartamento de Psiquiatria e Saúde Mental da Unidade Local de Saúde da Guarda, EPE, Guarda, PortugalDepartamento de Psiquiatria e Saúde Mental da Unidade Local de Saúde da Guarda, EPE, Guarda, PortugalDepartamento de Psiquiatria e Saúde Mental da Unidade Local de Saúde da Guarda, EPE, Guarda, PortugalDepartamento de Psiquiatria e Saúde Mental da Unidade Local de Saúde da Guarda, EPE, Guarda, PortugalDepartamento de Psiquiatria e Saúde Mental da Unidade Local de Saúde da Guarda, EPE, Guarda, Portugal Introduction: Antipsychotic polypharmacy (APP) and high dose (APHD) remain a common practice in the treatment of severe mental illness, even though they are not supported by current international guidelines. Methods: We aimed to establish the prescribing patterns of antipsychotics in a community mental health service in a rural setting, to determine the prevalence of APP and APHD treatment and to identify associated factors. Results: We identified 284 patients. APP was present in 46.5% patients and was associated to younger age, single status, more previous psychiatric admissions, and anticholinergic prescription. Prescription of APHD was observed in 14.4% patients and was associated with previous inpatient admissions, being prescribed with a first generation long‑acting injectable antipsychotic and anticholinergics. We also found that APP and APHD were mutually associated. Conclusion: Despite current guidelines, we found prevalences of APP and APHD of 46.5% and 14.4%, respectively. Further studies are necessary to better evaluate the antipsychotic prescription patterns in Portugal. https://www.revistapsiquiatria.pt/index.php/sppsm/article/view/163Antipsychotic AgentsCommunity Mental Health CentersInappropriate PrescribingPolypharmacy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sara Ramos Diana Cruz Bianca Jesus João Correia Isabel Vaz João Mendes |
spellingShingle |
Sara Ramos Diana Cruz Bianca Jesus João Correia Isabel Vaz João Mendes Antipsychotic Polypharmacy and High Doses in a Rural Portuguese Community Mental Health Service Revista Portuguesa de Psiquiatria e Saúde Mental Antipsychotic Agents Community Mental Health Centers Inappropriate Prescribing Polypharmacy |
author_facet |
Sara Ramos Diana Cruz Bianca Jesus João Correia Isabel Vaz João Mendes |
author_sort |
Sara Ramos |
title |
Antipsychotic Polypharmacy and High Doses in a Rural Portuguese Community Mental Health Service |
title_short |
Antipsychotic Polypharmacy and High Doses in a Rural Portuguese Community Mental Health Service |
title_full |
Antipsychotic Polypharmacy and High Doses in a Rural Portuguese Community Mental Health Service |
title_fullStr |
Antipsychotic Polypharmacy and High Doses in a Rural Portuguese Community Mental Health Service |
title_full_unstemmed |
Antipsychotic Polypharmacy and High Doses in a Rural Portuguese Community Mental Health Service |
title_sort |
antipsychotic polypharmacy and high doses in a rural portuguese community mental health service |
publisher |
Sociedade Portuguesa de Psiquiatria e Saúde Mental |
series |
Revista Portuguesa de Psiquiatria e Saúde Mental |
issn |
2184-5522 2184-5417 |
publishDate |
2021-09-01 |
description |
Introduction: Antipsychotic polypharmacy (APP) and high dose (APHD) remain a common practice in the treatment of severe mental illness, even though they are not supported by current international guidelines.
Methods: We aimed to establish the prescribing patterns of antipsychotics in a community mental health service in a rural setting, to determine the prevalence of APP and APHD treatment and to identify associated factors.
Results: We identified 284 patients. APP was present in 46.5% patients and was associated to younger age, single status, more previous psychiatric admissions, and anticholinergic prescription. Prescription of APHD was observed in 14.4% patients and was associated with previous inpatient admissions, being prescribed with a first generation long‑acting injectable antipsychotic and anticholinergics. We also found that APP and APHD were mutually associated.
Conclusion: Despite current guidelines, we found prevalences of APP and APHD of 46.5% and 14.4%, respectively. Further studies are necessary to better evaluate the antipsychotic prescription patterns in Portugal.
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topic |
Antipsychotic Agents Community Mental Health Centers Inappropriate Prescribing Polypharmacy |
url |
https://www.revistapsiquiatria.pt/index.php/sppsm/article/view/163 |
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