Dysregulation of chemokine receptor expression and function in leukocytes from ALS patients

Dysregulation of chemokine receptor expression and function in leukocytes from ALS patients

Abstract Amyotrophic lateral sclerosis (ALS) is rapidly progressive adult-onset motor neuron disease characterized by the neurodegeneration of both upper and lower motor neurons in the cortex and the spinal cord; the majority of patients succumb to respiratory failure. Although the etiology is not y...

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Bibliographic Details
Main Authors: Caroline Perner, Florian Perner, Beatrice Stubendorff, Martin Förster, Otto W. Witte, Florian H. Heidel, Tino Prell, Julian Grosskreutz
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Neuroinflammation
Subjects:
ALS
Chemokines
CXCR3
IP10
T cells
Online Access:http://link.springer.com/article/10.1186/s12974-018-1135-3

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