Successful Withdrawal of Omalizumab in a Patient with Severe Asthma: Free IgE as a Possible Biomonitor

Successful Withdrawal of Omalizumab in a Patient with Severe Asthma: Free IgE as a Possible Biomonitor

To date, the pharmacological activity and clinical benefits of omalizumab have been well described, however several questions still remain unanswered, such as the moment to withdraw the drug as well as the possible biological markers that may be useful to do so. In the present case report, we descri...

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Main Authors: C. Domingo, X. Pomares, M.-J. Amengual, M. Ollert
Format: Article
Language:English
Published: SAGE Publishing 2014-05-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X1401200217
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spelling doaj-c44dcdb5616140fdafec0413fc7783a72020-11-25T03:49:57ZengSAGE PublishingEuropean Journal of Inflammation1721-727X2014-05-011210.1177/1721727X1401200217Successful Withdrawal of Omalizumab in a Patient with Severe Asthma: Free IgE as a Possible BiomonitorC. Domingo0X. Pomares1M.-J. Amengual2M. Ollert3 Department of Medicine, Universitat Autònoma de Barcelona, Sabadell, Barcelona, Spain Department of Medicine, Universitat Autònoma de Barcelona, Sabadell, Barcelona, Spain Laboratory Departmanet, Immunology Section, UDIAT, Corporació Sanitària Universitària Parc Taulí, Sabadell, Barcelona, Spain Clinical Research Division of Molecular and Clinical Allergotoxicology, Department of Dermatology and Allergy, Technische Universität München, Munich, GermanyTo date, the pharmacological activity and clinical benefits of omalizumab have been well described, however several questions still remain unanswered, such as the moment to withdraw the drug as well as the possible biological markers that may be useful to do so. In the present case report, we describe our experience with our dose-reduction protocol in a middle-aged patient and elucidate the usefulness of free IgE levels.https://doi.org/10.1177/1721727X1401200217
collection DOAJ
language English
format Article
sources DOAJ
author C. Domingo
X. Pomares
M.-J. Amengual
M. Ollert
spellingShingle C. Domingo
X. Pomares
M.-J. Amengual
M. Ollert
Successful Withdrawal of Omalizumab in a Patient with Severe Asthma: Free IgE as a Possible Biomonitor
European Journal of Inflammation
author_facet C. Domingo
X. Pomares
M.-J. Amengual
M. Ollert
author_sort C. Domingo
title Successful Withdrawal of Omalizumab in a Patient with Severe Asthma: Free IgE as a Possible Biomonitor
title_short Successful Withdrawal of Omalizumab in a Patient with Severe Asthma: Free IgE as a Possible Biomonitor
title_full Successful Withdrawal of Omalizumab in a Patient with Severe Asthma: Free IgE as a Possible Biomonitor
title_fullStr Successful Withdrawal of Omalizumab in a Patient with Severe Asthma: Free IgE as a Possible Biomonitor
title_full_unstemmed Successful Withdrawal of Omalizumab in a Patient with Severe Asthma: Free IgE as a Possible Biomonitor
title_sort successful withdrawal of omalizumab in a patient with severe asthma: free ige as a possible biomonitor
publisher SAGE Publishing
series European Journal of Inflammation
issn 1721-727X
publishDate 2014-05-01
description To date, the pharmacological activity and clinical benefits of omalizumab have been well described, however several questions still remain unanswered, such as the moment to withdraw the drug as well as the possible biological markers that may be useful to do so. In the present case report, we describe our experience with our dose-reduction protocol in a middle-aged patient and elucidate the usefulness of free IgE levels.
url https://doi.org/10.1177/1721727X1401200217
work_keys_str_mv AT cdomingo successfulwithdrawalofomalizumabinapatientwithsevereasthmafreeigeasapossiblebiomonitor
AT xpomares successfulwithdrawalofomalizumabinapatientwithsevereasthmafreeigeasapossiblebiomonitor
AT mjamengual successfulwithdrawalofomalizumabinapatientwithsevereasthmafreeigeasapossiblebiomonitor
AT mollert successfulwithdrawalofomalizumabinapatientwithsevereasthmafreeigeasapossiblebiomonitor
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