Ocular masquerade syndrome associated with extranodal nasal natural killer/T-cell lymphoma: case report

• Main Authors: Ricardo Yuji Abe, Roberto Damian Pacheco Pinto, João Felipe Leite Bonfitto, Rodrigo Pessoa Cavalcanti Lira, Carlos Eduardo Leite Arieta
• Format: Article
• Language: English
• Published: Conselho Brasileiro de Oftalmologia
• Series: Arquivos Brasileiros de Oftalmologia
• Subjects: Neoplasias oculares; Linfoma de células T; Neoplasias nasaisl; Transtornos da visãol; Uveites; Neurite óptica; Células matadoras naturaisl; Imunoistoquímica; Humanos; Feminino; Adulto; Relato de caso
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492012000600013&lng=en&tlng=en

A 33-year-old woman complained of unilateral eyelid edema and blurred vision. Initial ophthalmic examination disclosed anterior chamber reaction with keratic precipitates on the cornea, without posterior abnormalities. Anterior uveitis was treated. Despite that, patient showed rapidly progressive unilateral vision loss with optic nerve swelling. Systemic workup was inconclusive, as well as cranial magnetic resonance imaging and cerebrospinal fluid examination. Based on the hypothesis of optic neuritis, intravenous methylprednisolone pulse was performed with no success. During the following days, the patient presented pericardial effusion and cardiac tamponade, progressing to death. Necropsy was performed and diagnosis of extranodal natural killers/T-cell lymphoma, nasal type with ocular involvement was confirmed by immunohistochemistry.