Enzyme kinetics and inhibition parameters of human leukocyte glucosylceramidase
Glucosylceramidase (GCase) is a lysosomal enzyme that catalyzes the cleavage of β-glucosidic linkage of glucocerebroside (GC) into glucose and ceramide; thereby, plays an essential function in the degradation of complex lipids and the turnover of cellular membranes.The growing list of 460 mutations...
Main Authors: | Mesut Karatas, Senol Dogan, Emrulla Spahiu, Adna Ašić, Larisa Bešić, Yusuf Turan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-11-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S240584402032034X |
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