Novel Genetic Variants of <i>ALG6</i> and <i>GALNTL4</i> of the Glycosylation Pathway Predict Cutaneous Melanoma-Specific Survival

Novel Genetic Variants of <i>ALG6</i> and <i>GALNTL4</i> of the Glycosylation Pathway Predict Cutaneous Melanoma-Specific Survival

Because aberrant glycosylation is known to play a role in the progression of melanoma, we hypothesize that genetic variants of glycosylation pathway genes are associated with the survival of cutaneous melanoma (CM) patients. To test this hypothesis, we used a Cox proportional hazards regression mode...

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Bibliographic Details
Main Authors: Bingrong Zhou, Yu Chen Zhao, Hongliang Liu, Sheng Luo, Christopher I. Amos, Jeffrey E. Lee, Xin Li, Hongmei Nan, Qingyi Wei
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
cutaneous melanoma
expression quantitative trait loci
glycosylation
single-nucleotide polymorphism
survival analysis
Online Access:https://www.mdpi.com/2072-6694/12/2/288

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