Intratracheal Poly(I:C) Exposure Accelerates the Immunological Disorder of Salivary Glands in Sjogren's-Like NOD/ShiLtJ Mice

Intratracheal Poly(I:C) Exposure Accelerates the Immunological Disorder of Salivary Glands in Sjogren's-Like NOD/ShiLtJ Mice

Evidences have suggested that Sjogren's syndrome (SS) is associated with viral infection. The aim of this study was to investigate the involvement of respiratory viral poly(I:C) in the pathogenesis of SS and potential mechanisms using a SS-like NOD/ShiLtJ (NOD) mouse model. 5-week female NOD mi...

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Bibliographic Details
Main Authors: Peng Hu, Bingxia Ming, Xuefen Wu, Shaozhe Cai, Jungen Tang, Yuanji Dong, Tianshu Zhou, Zheng Tan, Jixin Zhong, Fang Zheng, Lingli Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Medicine
Subjects:
Sjogren's syndrome
poly(I:C)
salivary gland
immune response
IL-33
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.645816/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.645816/full

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