Ethanol itself is a holoprosencephaly-inducing teratogen.
Ethanol is a teratogen, inducing a variety of structural defects in developing humans and animals that are exposed in utero. Mechanisms of ethanol teratogenicity in specific defects are not well understood. Oxidative metabolism of ethanol by alcohol dehydrogenase or cytochrome P450 2E1 has been impl...
Main Authors: | Mingi Hong, Robert S Krauss |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5404885?pdf=render |
Similar Items
-
Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice.
by: Mingi Hong, et al.
Published: (2012-01-01) -
Rescue of holoprosencephaly in fetal alcohol-exposed Cdon mutant mice by reduced gene dosage of Ptch1.
by: Mingi Hong, et al.
Published: (2013-01-01) -
Boc modifies the holoprosencephaly spectrum of Cdo mutant mice
by: Wei Zhang, et al.
Published: (2011-05-01) -
Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly
by: Mingi Hong, et al.
Published: (2020-09-01) -
Holoprosencephaly
by: Henry Catherine, et al.
Published: (2007-02-01)