Therapeutic Potential of Traditional Chinese Medicine on Inflammatory Diseases
Increased oxidative stress induces inflammation to several tissues/organs leading to cell death and long-term injury. Traditional Chinese Medicine (TCM) with antioxidant, anti-inflammatory, anti-apoptotic, and autophagic regulatory functions has been widely used as preventive or therapeutic strategy...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2013-07-01
|
Series: | Journal of Traditional and Complementary Medicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2225411016301857 |
id |
doaj-c4a4fba012fd404d83d5099e64395386 |
---|---|
record_format |
Article |
spelling |
doaj-c4a4fba012fd404d83d5099e643953862020-11-24T22:10:10ZengElsevierJournal of Traditional and Complementary Medicine2225-41102013-07-013314215110.4103/2225-4110.114898Therapeutic Potential of Traditional Chinese Medicine on Inflammatory DiseasesWen-Hsin Tsai0Chih-Ching Yang1Ping-Chia Li2Wang-Chuan Chen3Chiang-Ting Chien4Department of Traditional Chinese Medicine, Taipei City Hospital Linsen (Chinese Medicine) Branch, Taipei, Taiwan.Bureau of Planning, Department of Health, Executive Yuan, Taipei, Taiwan.Department of Occupational Therapy, I-Shou University, Kaohsiung, Taiwan.The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan.Department of Life Science, National Taiwan Normal University, Taipei, Taiwan.Increased oxidative stress induces inflammation to several tissues/organs leading to cell death and long-term injury. Traditional Chinese Medicine (TCM) with antioxidant, anti-inflammatory, anti-apoptotic, and autophagic regulatory functions has been widely used as preventive or therapeutic strategy in modern medicine. Oxidative stress and inflammation have been widely reported to contribute to cigarette smoke–induced lung inflammation, hepatotoxicity, or sympathetic activation–induced liver inflammation, lipopolysaccharide-induced renal inflammation, and substance P–mediated neurogenic hyperactive bladder based on clinical findings. In this review, we introduce several evidences for TCM treatment including Monascus adlay (MA) produced by inoculating adlay (Cois lachrymal-jobi L. var. ma-yuen Stapf) with Monascus purpureus on lung injury, Amla (Emblica officinalis Gaertn. of Euphorbiaceae family) on hepatotoxin-induced liver inflammation, Virgate Wormwood Decoction (茵陳蒿湯 Yīn Chén Hāo tāng) and its active component genipin on sympathetic activation–induced liver inflammation, and green tea extract and its active components, catechins, or a modified TCM formula Five Stranguries Powder (五淋散 Wǔ Lín Sǎn) plus Crataegi Fructus (山楂 Shān Zhā) on hyperactive bladder. The pathophysiologic and molecular mechanisms of TCM on ameliorating inflammatory diseases are discussed in the review.http://www.sciencedirect.com/science/article/pii/S2225411016301857ApoptosisAutophagyEndoplasmic reticulum stressInflammationOxidative stressTraditional Chinese Medicine |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Wen-Hsin Tsai Chih-Ching Yang Ping-Chia Li Wang-Chuan Chen Chiang-Ting Chien |
spellingShingle |
Wen-Hsin Tsai Chih-Ching Yang Ping-Chia Li Wang-Chuan Chen Chiang-Ting Chien Therapeutic Potential of Traditional Chinese Medicine on Inflammatory Diseases Journal of Traditional and Complementary Medicine Apoptosis Autophagy Endoplasmic reticulum stress Inflammation Oxidative stress Traditional Chinese Medicine |
author_facet |
Wen-Hsin Tsai Chih-Ching Yang Ping-Chia Li Wang-Chuan Chen Chiang-Ting Chien |
author_sort |
Wen-Hsin Tsai |
title |
Therapeutic Potential of Traditional Chinese Medicine on Inflammatory Diseases |
title_short |
Therapeutic Potential of Traditional Chinese Medicine on Inflammatory Diseases |
title_full |
Therapeutic Potential of Traditional Chinese Medicine on Inflammatory Diseases |
title_fullStr |
Therapeutic Potential of Traditional Chinese Medicine on Inflammatory Diseases |
title_full_unstemmed |
Therapeutic Potential of Traditional Chinese Medicine on Inflammatory Diseases |
title_sort |
therapeutic potential of traditional chinese medicine on inflammatory diseases |
publisher |
Elsevier |
series |
Journal of Traditional and Complementary Medicine |
issn |
2225-4110 |
publishDate |
2013-07-01 |
description |
Increased oxidative stress induces inflammation to several tissues/organs leading to cell death and long-term injury. Traditional Chinese Medicine (TCM) with antioxidant, anti-inflammatory, anti-apoptotic, and autophagic regulatory functions has been widely used as preventive or therapeutic strategy in modern medicine. Oxidative stress and inflammation have been widely reported to contribute to cigarette smoke–induced lung inflammation, hepatotoxicity, or sympathetic activation–induced liver inflammation, lipopolysaccharide-induced renal inflammation, and substance P–mediated neurogenic hyperactive bladder based on clinical findings. In this review, we introduce several evidences for TCM treatment including Monascus adlay (MA) produced by inoculating adlay (Cois lachrymal-jobi L. var. ma-yuen Stapf) with Monascus purpureus on lung injury, Amla (Emblica officinalis Gaertn. of Euphorbiaceae family) on hepatotoxin-induced liver inflammation, Virgate Wormwood Decoction (茵陳蒿湯 Yīn Chén Hāo tāng) and its active component genipin on sympathetic activation–induced liver inflammation, and green tea extract and its active components, catechins, or a modified TCM formula Five Stranguries Powder (五淋散 Wǔ Lín Sǎn) plus Crataegi Fructus (山楂 Shān Zhā) on hyperactive bladder. The pathophysiologic and molecular mechanisms of TCM on ameliorating inflammatory diseases are discussed in the review. |
topic |
Apoptosis Autophagy Endoplasmic reticulum stress Inflammation Oxidative stress Traditional Chinese Medicine |
url |
http://www.sciencedirect.com/science/article/pii/S2225411016301857 |
work_keys_str_mv |
AT wenhsintsai therapeuticpotentialoftraditionalchinesemedicineoninflammatorydiseases AT chihchingyang therapeuticpotentialoftraditionalchinesemedicineoninflammatorydiseases AT pingchiali therapeuticpotentialoftraditionalchinesemedicineoninflammatorydiseases AT wangchuanchen therapeuticpotentialoftraditionalchinesemedicineoninflammatorydiseases AT chiangtingchien therapeuticpotentialoftraditionalchinesemedicineoninflammatorydiseases |
_version_ |
1725808875869831168 |