A novel role for IkappaBzeta in the regulation of IFNgamma production.
IkappaBzeta is a novel member of the IkappaB family of NFkappaB regulators, which modulates NFkappaB activity in the nucleus, rather than controlling its nuclear translocation. IkappaBzeta is specifically induced by IL-1beta and several TLR ligands and positively regulates NFkappaB-mediated transcri...
Main Authors: | Raquel M Raices, Yashaswini Kannan, Vedavathi Bellamkonda-Athmaram, Sudarshan Seshadri, Huating Wang, Denis C Guttridge, Mark D Wewers |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-08-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2727951?pdf=render |
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