Single nucleotide variants in immune-response genes and the tumor microenvironment composition predict progression of mantle cell lymphoma

Single nucleotide variants in immune-response genes and the tumor microenvironment composition predict progression of mantle cell lymphoma

Abstract Background There is evidence to consider that the tumor microenvironment (TME) composition associates with antitumor immune response, and may predict the outcome of various non-Hodgkin lymphoma subtypes. However, in the case of mantle cell lymphoma (MCL), a rare and aggressive disease, ther...

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Main Authors: Guilherme Rossi Assis-Mendonça, André Fattori, Rafael Malagoli Rocha, Gustavo Jacob Lourenço, Márcia Torresan Delamain, Suely Nonogaki, Vladmir Cláudio Cordeiro de Lima, Gisele Wally Braga Colleoni, Cármino Antonio de Souza, Fernando Augusto Soares, Carmen Silvia Passos Lima, José Vassallo
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Cancer
Subjects:
Mantle cell lymphoma
Tumor microenvironment
SNVs
Immunohistochemistry
Prognostic factors
Online Access:https://doi.org/10.1186/s12885-021-07891-9

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