syn-Selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysis

syn-Selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysis

Converting alkynes into alkenes with high stereoselectivity via two consecutive C-C bond forming steps is a desirable process, yet very challenging. Here, the authors describe a dual photoredox-nickel catalytic system for the regio- and syn-selective alkylarylation of terminal alkynes with alkyl oxa...

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Main Authors: Lei Guo, Fan Song, Shengqing Zhu, Huan Li, Lingling Chu
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06904-9
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spelling doaj-c4f51708a4e34e558cb4dc711bb94cf02021-05-11T10:08:49ZengNature Publishing GroupNature Communications2041-17232018-10-01911810.1038/s41467-018-06904-9syn-Selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysisLei Guo0Fan Song1Shengqing Zhu2Huan Li3Lingling Chu4State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Center for Advanced Low-Dimension Materials, Donghua UniversityConverting alkynes into alkenes with high stereoselectivity via two consecutive C-C bond forming steps is a desirable process, yet very challenging. Here, the authors describe a dual photoredox-nickel catalytic system for the regio- and syn-selective alkylarylation of terminal alkynes with alkyl oxalates and aryl bromides.https://doi.org/10.1038/s41467-018-06904-9
collection DOAJ
language English
format Article
sources DOAJ
author Lei Guo
Fan Song
Shengqing Zhu
Huan Li
Lingling Chu
spellingShingle Lei Guo
Fan Song
Shengqing Zhu
Huan Li
Lingling Chu
syn-Selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysis
Nature Communications
author_facet Lei Guo
Fan Song
Shengqing Zhu
Huan Li
Lingling Chu
author_sort Lei Guo
title syn-Selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysis
title_short syn-Selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysis
title_full syn-Selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysis
title_fullStr syn-Selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysis
title_full_unstemmed syn-Selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysis
title_sort syn-selective alkylarylation of terminal alkynes via the combination of photoredox and nickel catalysis
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-10-01
description Converting alkynes into alkenes with high stereoselectivity via two consecutive C-C bond forming steps is a desirable process, yet very challenging. Here, the authors describe a dual photoredox-nickel catalytic system for the regio- and syn-selective alkylarylation of terminal alkynes with alkyl oxalates and aryl bromides.
url https://doi.org/10.1038/s41467-018-06904-9
work_keys_str_mv AT leiguo synselectivealkylarylationofterminalalkynesviathecombinationofphotoredoxandnickelcatalysis
AT fansong synselectivealkylarylationofterminalalkynesviathecombinationofphotoredoxandnickelcatalysis
AT shengqingzhu synselectivealkylarylationofterminalalkynesviathecombinationofphotoredoxandnickelcatalysis
AT huanli synselectivealkylarylationofterminalalkynesviathecombinationofphotoredoxandnickelcatalysis
AT linglingchu synselectivealkylarylationofterminalalkynesviathecombinationofphotoredoxandnickelcatalysis
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