Association between age associated cognitive decline and health related quality of life among Iranian older individuals
Background: Age associated cognitive decline or normal cognitive aging is related with lower levels of functioning in real life, and may interfere with maintaining independence and health related quality of life (HRQL). Objective: In this study, health related quality of life and cognitive functi...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Electronic Physician
2018-04-01
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Series: | Electronic Physician |
Subjects: | |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984021/ |
Summary: | Background: Age associated cognitive decline or normal cognitive aging is related with lower levels of
functioning in real life, and may interfere with maintaining independence and health related quality of life
(HRQL).
Objective: In this study, health related quality of life and cognitive function in community-dwelling older adults
were evaluated with the aim of exploring the association between them by adjusting for potential confounders.
Methods: This cross-sectional study, was implemented on 425 community-dwelling older adults aged 60 and
over, between August 2016 and October 2016 in health centers of the municipality of Tehran, Iran, using Mini
Mental State Examination (MMSE) to assess cognitive function and Short Form-36 scales (SF-36) to assess
HRQL. The relation between HRQL and cognitive function was evaluated by Pearson’s correlation coefficient,
and the impact of cognitive function on HRQL adjusted for potential confounders was estimated by linear
regression model. All analyses were done using SPSS, version 22.0.
Results: A positive significant correlation between cognitive function and quality of life (r=0.434; p<0.001) and
its dimensions was observed. Two variables of educational level (B=2.704; 95% CI: 2.09 to 3.30; p<0.001) and
depression (B=2.554; 95% CI: 2.00 to 3.10; p<0.001) were assumed as potential confounder by changing effect
measure after entering the model. After adjusting for potential confounders in regression model, the association
between MMSE scores and quality of life persisted (B=2.417; 95% CI: 1.86 to 2.96; p<0.001).
Conclusion: The results indicate that cognitive function was associated with HRQL in older adults with age
associated cognitive function. Two variables of educational level and depression can affect the relation between
cognitive decline and HRQL. |
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ISSN: | 2008-5842 2008-5842 |