BAMBI is expressed in endothelial cells and is regulated by lysosomal/autolysosomal degradation.

BAMBI (BMP and Activin Membrane Bound Inhibitor) is considered to influence TGFβ and Wnt signaling, and thereby fibrosis. Surprisingly data on cell type-specific expression of BAMBI are not available. We therefore examined the localization, gene regulation, and protein turnover of BAMBI in kidneys.B...

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Bibliographic Details
Main Authors: Sandhya Xavier, Victoria Gilbert, Maria Pia Rastaldi, Stefanie Krick, Dmitrij Kollins, Anand Reddy, Erwin Bottinger, Clemens D Cohen, Detlef Schlondorff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2945319?pdf=render