Species-Dependent Functionality of the Human Cytolytic Fusion Proteins Granzyme B-H22(scFv) and H22(scFv)-Angiogenin in Macrophages
Human cytolytic fusion proteins (hCFPs) are comprised of a specific cell-surface-binding moiety and an effector molecule of human origin. In contrast to common immunotoxins, including bacterial or plant toxins, they are considered not to be immunogenic. Two examples for human pro-apoptotic effector...
Main Authors: | Theo Thepen, Stefan Barth, Rainer Fischer, Michael Huhn, Radoslav Mladenov, Eric Aslanian, Dmitrij Hristodorov, Sonja Schiffer |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-01-01
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Series: | Antibodies |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4468/2/1/9 |
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