Switchable stimulated Raman scattering microscopy with photochromic vibrational probes
Probes with reversible fluorescence are useful in super-resolution microscopy, but lack sufficient chemical specificity. Here, the authors engineer alkyne tagged diarylethene to realize photo-switchable stimulated Raman scattering probes with high chemical resolution, for applications in living cell...
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2021-05-01
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Online Access: | https://doi.org/10.1038/s41467-021-23407-2 |
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doaj-c5313c376b384dc4ba4f35c784df37312021-05-30T11:14:38ZengNature Publishing GroupNature Communications2041-17232021-05-011211810.1038/s41467-021-23407-2Switchable stimulated Raman scattering microscopy with photochromic vibrational probesJianpeng Ao0Xiaofeng Fang1Xianchong Miao2Jiwei Ling3Hyunchul Kang4Sungnam Park5Changfeng Wu6Minbiao Ji7State Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Multiscale Research Institute of Complex Systems, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan UniversityDepartment of Biomedical Engineering, Southern University of Science and TechnologyState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Multiscale Research Institute of Complex Systems, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan UniversityState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Multiscale Research Institute of Complex Systems, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan UniversityDepartment of Chemistry and Research Institute for Natural Science, Korea UniversityDepartment of Chemistry and Research Institute for Natural Science, Korea UniversityDepartment of Biomedical Engineering, Southern University of Science and TechnologyState Key Laboratory of Surface Physics and Department of Physics, Human Phenome Institute, Multiscale Research Institute of Complex Systems, Academy for Engineering and Technology, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), Fudan UniversityProbes with reversible fluorescence are useful in super-resolution microscopy, but lack sufficient chemical specificity. Here, the authors engineer alkyne tagged diarylethene to realize photo-switchable stimulated Raman scattering probes with high chemical resolution, for applications in living cells.https://doi.org/10.1038/s41467-021-23407-2 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jianpeng Ao Xiaofeng Fang Xianchong Miao Jiwei Ling Hyunchul Kang Sungnam Park Changfeng Wu Minbiao Ji |
spellingShingle |
Jianpeng Ao Xiaofeng Fang Xianchong Miao Jiwei Ling Hyunchul Kang Sungnam Park Changfeng Wu Minbiao Ji Switchable stimulated Raman scattering microscopy with photochromic vibrational probes Nature Communications |
author_facet |
Jianpeng Ao Xiaofeng Fang Xianchong Miao Jiwei Ling Hyunchul Kang Sungnam Park Changfeng Wu Minbiao Ji |
author_sort |
Jianpeng Ao |
title |
Switchable stimulated Raman scattering microscopy with photochromic vibrational probes |
title_short |
Switchable stimulated Raman scattering microscopy with photochromic vibrational probes |
title_full |
Switchable stimulated Raman scattering microscopy with photochromic vibrational probes |
title_fullStr |
Switchable stimulated Raman scattering microscopy with photochromic vibrational probes |
title_full_unstemmed |
Switchable stimulated Raman scattering microscopy with photochromic vibrational probes |
title_sort |
switchable stimulated raman scattering microscopy with photochromic vibrational probes |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2021-05-01 |
description |
Probes with reversible fluorescence are useful in super-resolution microscopy, but lack sufficient chemical specificity. Here, the authors engineer alkyne tagged diarylethene to realize photo-switchable stimulated Raman scattering probes with high chemical resolution, for applications in living cells. |
url |
https://doi.org/10.1038/s41467-021-23407-2 |
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