Eosinophilic Fasciitis: A Case Report and Literature Review

• Main Authors: Charussri Leeyaphan, Kanokvalai Kulthanan, Panitta Sitthinamsuwan, Nisa Kiewjoy
• Format: Article
• Language: English
• Published: Mahidol University 2020-07-01
• Series: Siriraj Medical Journal
• Subjects: Eosinophilic fasciitis; scleroderma-like syndrome
• Online Access: https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/243896

Eosinophilic fasciitis (EF) is a rare scleroderma-like syndrome. There has been no previous published report of EF in a Thai patient. We described a 41 year-old Thai man who presented with symmetric induration of the skin of forearms, arms, hands, fingers, lower aspects of the legs, and feet. Physical examination revealed bilateral symmetrical woody induration of the skin with peau d’orange appearance. A groove sign was positive on the flexural surface of both arms. Laboratory testing revealed a peripheral eosinophil count of 54%. The skin and superficial fascia biopsy specimen from the inner aspect of the left forearm was consistent with EF. He was treated with prednisolone, methotrexate, and colchicine. He experienced a gradual improvement within 4 months. A history of acute onset of scleroderma-like syndrome and careful physical examination can lead us to the diagnosis of EF.