Hydrophilic Biocompatible Poly(Acrylic Acid-co-Maleic Acid) Polymer as a Surface-Coating Ligand of Ultrasmall Gd<sub>2</sub>O<sub>3</sub> Nanoparticles to Obtain a High r<sub>1</sub> Value and T<sub>1</sub> MR Images

Hydrophilic Biocompatible Poly(Acrylic Acid-co-Maleic Acid) Polymer as a Surface-Coating Ligand of Ultrasmall Gd<sub>2</sub>O<sub>3</sub> Nanoparticles to Obtain a High r<sub>1</sub> Value and T<sub>1</sub> MR Images

The water proton spin relaxivity, colloidal stability, and biocompatibility of nanoparticle-based magnetic resonance imaging (MRI) contrast agents depend on the surface-coating ligands. Here, poly(acrylic acid-co-maleic acid) (PAAMA) (M<sub>w</sub> = ~3000 amu) is explored as a surface-c...

Full description

Bibliographic Details
Main Authors:	Yeong-Ji Jang, Shuwen Liu, Huan Yue, Ji Ae Park, Hyunsil Cha, Son Long Ho, Shanti Marasini, Adibehalsadat Ghazanfari, Mohammad Yaseen Ahmad, Xu Miao, Tirusew Tegafaw, Kwon-Seok Chae, Yongmin Chang, Gang Ho Lee
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Series:	Diagnostics
Subjects:	poly(acrylic acid-co-maleic acid) ultrasmall Gd<sub>2</sub>O<sub>3</sub> nanoparticle relaxivity colloidal stability biocompatibility magnetic resonance imaging agent
Online Access:	https://www.mdpi.com/2075-4418/11/1/2

Similar Items

Polyaspartic Acid-Coated Paramagnetic Gadolinium Oxide Nanoparticles as a Dual-Modal T<sub>1</sub> and T<sub>2</sub> Magnetic Resonance Imaging Contrast Agent
by: Shanti Marasini, et al.
Published: (2021-09-01)

Synthesis, Characterizations, and 9.4 Tesla T<sub>2</sub> MR Images of Polyacrylic Acid-Coated Terbium(III) and Holmium(III) Oxide Nanoparticles
by: Shanti Marasini, et al.
Published: (2021-05-01)

In Vivo Positive Magnetic Resonance Imaging Applications of Poly(methyl vinyl ether-alt-maleic acid)-coated Ultra-small Paramagnetic Gadolinium Oxide Nanoparticles
by: Mohammad Yaseen Ahmad, et al.
Published: (2020-03-01)

First-Principles Study of Thermo-Physical Properties of Pu-Containing Gd<sub>2</sub>Zr<sub>2</sub>O<sub>7</sub>
by: Pengcheng Li, et al.
Published: (2019-02-01)

Active, Selective, and Recyclable Zr(SO<sub>4</sub>)<sub>2</sub>/SiO<sub>2</sub> and Zr(SO<sub>4</sub>)<sub>2</sub>/Activated Carbon Solid Acid Catalysts for Esterification of Malic Acid to Dimethyl Malate
by: Pei Yu, et al.
Published: (2020-04-01)

Optimization of Yb<sub>2</sub>O<sub>3</sub>-Gd<sub>2</sub>O<sub>3</sub>-Y<sub>2</sub>O<sub>3</sub> Co-Doped ZrO<sub>2</sub> Agglomerated and Calcined Powders for Air Plasma Spraying
by: Zheng Yan, et al.
Published: (2021-03-01)

Switching Characteristics and Mechanism Using Al<sub>2</sub>O<sub>3</sub> Interfacial Layer in Al/Cu/GdO<sub>x</sub>/Al<sub>2</sub>O<sub>3</sub>/TiN Memristor
by: Chiao-Fan Chiu, et al.
Published: (2020-09-01)

Structural Evolution and Magnetic Properties of Gd<sub>2</sub>Hf<sub>2</sub>O<sub>7</sub> Nanocrystals: Computational and Experimental Investigations
by: Madhab Pokhrel, et al.
Published: (2020-10-01)

Rapid Immobilization of Simulated Radioactive Soil Waste Using Self-Propagating Synthesized Gd<sub>2</sub>Ti<sub>2</sub>O<sub>7</sub> Pyrochlore Matrix
by: Jiali Xue, et al.
Published: (2019-04-01)

Molecular Dynamics Studies of Poly(Lactic Acid) Nanoparticles and Their Interactions with Vitamin E and TLR Agonists Pam<sub>1</sub>CSK<sub>4 </sub>and Pam<sub>3</sub>CSK<sub>4</sub>
by: Simon Megy, et al.
Published: (2020-11-01)

New Class of Efficient T<sub>2</sub> Magnetic Resonance Imaging Contrast Agent: Carbon-Coated Paramagnetic Dysprosium Oxide Nanoparticles
by: Huan Yue, et al.
Published: (2020-10-01)

Bi<sub>2</sub>S<sub>3</sub>/rGO Composite Based Electrochemical Sensor for Ascorbic Acid Detection
by: Chengling Qu, et al.
Published: (2021-07-01)

Surface-Bound Humic Acid Increased Propranolol Sorption on Fe<sub>3</sub>O<sub>4</sub>/Attapulgite Magnetic Nanoparticles
by: Yuehua Deng, et al.
Published: (2020-01-01)

Ca-Poisoning Effect on V<sub>2</sub>O<sub>5</sub>-WO<sub>3</sub>/TiO<sub>2</sub> and V<sub>2</sub>O<sub>5</sub>-WO<sub>3</sub>-CeO<sub>2</sub>/TiO<sub>2</sub> Catalysts with Different Vanadium Loading
by: Yangyang Guo, et al.
Published: (2021-03-01)

Na<sub>2</sub>SO<sub>4</sub> + V<sub>2</sub>O<sub>5</sub> Corrosion Behavior of BaNd<sub>2</sub>Ti<sub>3</sub>O<sub>10</sub> for Thermal Barrier Coating Applications
by: Yajuan She, et al.
Published: (2020-09-01)

{CeO<sub>2</sub>/Bi<sub>2</sub>Mo<sub>1−x</sub>Ru<sub>x</sub>O<sub>6</sub>} and {Au/Bi<sub>2</sub>Mo<sub>1−x</sub>Ru<sub>x</sub>O<sub>6</sub>} Catalysts for Low-Temperature CO Oxidation
by: Edson Edain González, et al.
Published: (2019-11-01)

Synthesis of Green-Emitting Gd<sub>2</sub>O<sub>2</sub>S:Pr<sup>3+</sup> Phosphor Nanoparticles and Fabrication of Translucent Gd<sub>2</sub>O<sub>2</sub>S:Pr<sup>3+</sup> Scintillation Ceramics
by: Zhigang Sun, et al.
Published: (2020-08-01)

Facile One-Step Hydrothermal Fabrication of (Sr<sub>0.6</sub>Bi<sub>0.305</sub>)<sub>2</sub>Bi<sub>2</sub>O<sub>7</sub>/SnO<sub>2</sub> Heterojunction with Excellent Photocatalytic Activity
by: Di Zhu, et al.
Published: (2020-02-01)

Magnetic Properties of Li<sub>3</sub>V<sub>2</sub>(PO<sub>4</sub>)<sub>3</sub>/Li<sub>3</sub>PO<sub>4</sub> Composite
by: Tatiana Gavrilova, et al.
Published: (2021-05-01)

Dehydrogenation of Formic Acid to CO<sub>2</sub> and H<sub>2</sub> by Manganese(I)–Complex: Theoretical Insights for Green and Sustainable Route
by: Tiziana Marino, et al.
Published: (2021-01-01)

Effect of Fe<sub>2</sub>O<sub>3</sub> on Electro-Deoxidation in Fe<sub>2</sub>O<sub>3</sub>-Al<sub>2</sub>O<sub>3</sub>-NaCl-KCl System
by: Yanke Xu, et al.
Published: (2021-08-01)

Preparation, Thermal, and Physical Properties of Perovskite-Type (C<sub>3</sub>H<sub>7</sub>NH<sub>3</sub>)<sub>2</sub>CdCl<sub>4</sub> Crystals
by: Ae Ran Lim, et al.
Published: (2019-02-01)

Facile Charge Transfer between Barbituric Acid and Chloranilic Acid over g-C<sub>3</sub>N<sub>4</sub>: Synthesis, Characterization and DFT Study
by: Gaber A. M. Mersal, et al.
Published: (2021-06-01)

AgBr/(Sr<sub>0.6</sub>Bi<sub>0.305</sub>)<sub>2</sub>Bi<sub>2</sub>O<sub>7</sub> Heterostructured Composites: Fabrication, Characterization, and Significantly Enhanced Photocatalytic Activity
by: Xinling Wang, et al.
Published: (2019-04-01)

The Influence of Oxygen Concentration during MAX Phases (Ti<sub>3</sub>AlC<sub>2</sub>) Preparation on the α-Al<sub>2</sub>O<sub>3</sub> Microparticles Content and Specific Surface Area of Multilayered MXenes (Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub>)
by: Błażej Scheibe, et al.
Published: (2019-01-01)

Improved NOx Reduction Using C<sub>3</sub>H<sub>8</sub> and H<sub>2</sub> with Ag/Al<sub>2</sub>O<sub>3</sub> Catalysts Promoted with Pt and WOx
by: Naomi N. González Hernández, et al.
Published: (2020-10-01)

Hydrogen Production from Formic Acid over Au Catalysts Supported on Carbon: Comparison with Au Catalysts Supported on SiO<sub>2</sub> and Al<sub>2</sub>O<sub>3</sub>
by: Dmitri A. Bulushev, et al.
Published: (2019-04-01)

Kinetic and Mechanistic Study of Rhodamine B Degradation by H<sub>2</sub>O<sub>2</sub> and Cu/Al<sub>2</sub>O<sub>3</sub>/g-C<sub>3</sub>N<sub>4</sub> Composite
by: Chunsun Zhou, et al.
Published: (2020-03-01)

Effect of SO<sub>2</sub> on the Selective Catalytic Reduction of NO<i><sub>x</sub></i> over V<sub>2</sub>O<sub>5</sub>-CeO<sub>2</sub>/TiO<sub>2</sub>-ZrO<sub>2</sub> Catalysts
by: Yaping Zhang, et al.
Published: (2019-08-01)

Effect of Zirconia on Hydrothermally Synthesized Co<sub>3</sub>O<sub>4</sub>/TiO<sub>2</sub> Catalyst for NO<sub>x</sub> Reduction from Engine Emissions
by: Muhammad Habib Ur Rehman, et al.
Published: (2020-02-01)

Tribological Properties of ZnS(NH<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>NH<sub>2</sub>)<sub>0.5</sub> and ZnS as Additives in Lithium Grease
by: Aoxiang Lu, et al.
Published: (2019-03-01)

Corrosion Behavior of Amorphous Sol–Gel TiO<sub>2</sub>–ZrO<sub>2</sub> Nano Thickness Film on Stainless Steel
by: Lidija Ćurković, et al.
Published: (2021-08-01)

Structural and photocatalytic properties of rice granular CaIn<sub>2</sub>O<sub>4</sub>/In<sub>2</sub>O<sub>3</sub> fabricated by electrospinning
by: ZHANG Qin-ku, et al.
Published: (2020-11-01)

New Perspectives on the Electronic and Geometric Structure of Au<sub>70</sub>S<sub>20</sub>(PPh<sub>3</sub>)<sub>12</sub> Cluster: Superatomic-Network Core Protected by Novel Au<sub>12</sub>(µ<sub>3</sub>-S)<sub>10</sub> Staple Motifs
by: Zhimei Tian, et al.
Published: (2019-08-01)

Microstructure Evolution and Properties of an In-Situ Nano-Gd<sub>2</sub>O<sub>3</sub>/Cu Composite by Powder Metallurgy
by: Haiyao Cao, et al.
Published: (2021-09-01)

CO<sub>2</sub> Hydrogenation on Ni<sub>x</sub>Mg<sub>1−x</sub>Al<sub>2</sub>O<sub>4</sub>: A Comparative Study of MgAl<sub>2</sub>O<sub>4</sub> and NiAl<sub>2</sub>O<sub>4</sub>
by: Boseok Seo, et al.
Published: (2021-08-01)

Solution-Based Synthesis of Sulvanite Cu<sub>3</sub>TaS<sub>4</sub> and Cu<sub>3</sub>TaSe<sub>4</sub> Nanocrystals
by: Mimi Liu, et al.
Published: (2021-01-01)

Synthesis of an Ag<sub>3</sub>PO<sub>4</sub>/Nb<sub>2</sub>O<sub>5</sub> Photocatalyst for the Degradation of Dye
by: Nur Syazwani Osman, et al.
Published: (2021-04-01)

Effect of ludwigite (B<sub>2</sub>O<sub>3</sub>) on high Al<sub>2</sub>O<sub>3</sub> slag and its mechanism used as a new blast furnace welding flux
by: B. Dai, et al.
Published: (2020-01-01)

A Novel Drug Design Strategy: An Inspiration from Encaging Tumor by Metallofullerenol Gd@C<sub>82</sub>(OH)<sub>22</sub>
by: Jinxia Li, et al.
Published: (2019-06-01)