The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies
Summary: Cofilins are important for the regulation of the actin cytoskeleton, sarcomere organization, and force production. The role of cofilin-1, the non-muscle-specific isoform, in muscle function remains unclear. Mutations in LMNA encoding A-type lamins, intermediate filament proteins of the nucl...
Main Authors: | Nicolas Vignier, Maria Chatzifrangkeskou, Luca Pinton, Hugo Wioland, Thibaut Marais, Mégane Lemaitre, Caroline Le Dour, Cécile Peccate, Déborah Cardoso, Alain Schmitt, Wei Wu, Maria-Grazia Biferi, Naïra Naouar, Coline Macquart, Maud Beuvin, Valérie Decostre, Gisèle Bonne, Guillaume Romet-Lemonne, Howard J. Worman, Francesco Saverio Tedesco, Antoine Jégou, Antoine Muchir |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-08-01
|
Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124721010391 |
Similar Items
-
The Pathogenesis and Therapies of Striated Muscle Laminopathies
by: Astrid Brull, et al.
Published: (2018-10-01) -
Need for NAD<sup>+</sup>: Focus on Striated Muscle Laminopathies
by: Déborah Cardoso, et al.
Published: (2020-10-01) -
Cellular and Animal Models of Striated Muscle Laminopathies
by: Hannah A. Nicolas, et al.
Published: (2019-03-01) -
Skeletal Muscle Laminopathies: A Review of Clinical and Molecular Features
by: Lorenzo Maggi, et al.
Published: (2016-08-01) -
Effect of genetic background on the cardiac phenotype in a mouse model of Emery-Dreifuss muscular dystrophy
by: Nicolas Vignier, et al.
Published: (2019-09-01)