First report of evaluation of K-M media: A new corneal preservation medium

• Main Authors: Desai Beena, Khamar B, Ghodadra B
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2007-01-01
• Series: Indian Journal of Ophthalmology
• Subjects: Corneal preservation media; donor cornea; Kalevar-Majumdar medium; moist chamber; pseudophakic bullous keratopathy
• Online Access: http://www.ijo.in/article.asp?issn=0301-4738;year=2007;volume=55;issue=1;spage=43;epage=47;aulast=Desai

<b>Purpose: </b> To analyze the outcome of keratoplasty performed using Kalevar-Majumdar (K-M) media, a new synthetic viscous medium for preservation of the cornea. <b> Materials and Methods:</b> The K-M media-preserved donor eye balls were kept in a bottle in a refrigerator at 4&#x00B0; C till the corneas were used. Forty-eight consecutive keratoplasty cases of pseudophakic bullous keratopathy with vision less than counting fingers at one meter and operated by a single surgeon have been analyzed. Corneal donor button of 7.5 mm was used on the 7.0 mm recipient bed in all cases. Surgery was done with a standard technique. All the cases were examined daily for the first week and at the end of one month for graft clarity, epithelial defect and stromal edema. <b> Results:</b> The K-M media-preserved corneal grafts remained clear at the end of the first week in 95.8&#x0025; (46 of 48) cases and at the end of one month in 93.7&#x0025; (45 of 48) cases. Donor epithelial haze cleared in 24h in all cases. The stromal edema got cleared in the majority (91.7&#x0025;, 44 of 48) within 24h. Epithelial defect was seen in only 10.4&#x0025; (five cases). There was no primary graft failure. <b> Conclusion:</b> K-M medium, a new viscous, synthetic corneal preservation medium, is a safe (no primary donor failure) alternative to conventional liquid corneal preservation media. K-M media-preserved eyes appear to have better preserved corneal epithelium with faster achievement of graft clarity postoperatively.