Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation
Vitamin B12 is an essential vitamin for metabolism of carbohydrates, protein and fat. It is also required for proper functioning of nervous system. Skin hyper pigmentation, hair changes, vitiligo and angular stomatitis are cutaneous manifestations of vitamin B12 deficiency. Hyper pigmentation in Ind...
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Deccan College of Medical Sciences
2018-01-01
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doaj-c56f9b464fe1436dbcd2c4be9c23a9002020-11-25T01:30:38ZengDeccan College of Medical SciencesJournal of Medical and Allied Sciences2231-16962231-170X2018-01-0181495210.5455/jmas.275238275238Vitamin B12 deficiency causing neurological syndrome with rare skin manifestationSamreen Fathima0Tukaram Umesh1Deccan College of Medical Sciences, Kanchanbagh, Hyderabad-500058, Telangana, India Department of Neurology, Deccan College of Medical Sciences, Kanchanbagh, Hyderabad-500058, Telangana, India.Vitamin B12 is an essential vitamin for metabolism of carbohydrates, protein and fat. It is also required for proper functioning of nervous system. Skin hyper pigmentation, hair changes, vitiligo and angular stomatitis are cutaneous manifestations of vitamin B12 deficiency. Hyper pigmentation in Indian patients as first presentation of this deficiency is rarely reported. Our case was a 39-year-old lady who has presented with selective dark hyperpigmentation of hands and feet with electrophysiological evidence of peripheral neuropathy and biochemically proven vitamin B12 deficiency. Skin manifestation was reversed with intramuscular vitamin B12 administration of 1000mcg for 6 weeks. This case emphasizes the importance of rare skin presentation of reversible condition. It also marks the necessity of understanding all aspects and presentations of vitamin B12. Role of nutritional aspects of a person and their importance to prevent neurological sequel is discussed. [J Med Allied Sci 2018; 8(1.000): 49-52]http://www.ejmanager.com/fulltextpdf.php?mno=275238Cutaneous manifestationsNeurological manifestationsVitamin B12 deficiency |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Samreen Fathima Tukaram Umesh |
spellingShingle |
Samreen Fathima Tukaram Umesh Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation Journal of Medical and Allied Sciences Cutaneous manifestations Neurological manifestations Vitamin B12 deficiency |
author_facet |
Samreen Fathima Tukaram Umesh |
author_sort |
Samreen Fathima |
title |
Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation |
title_short |
Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation |
title_full |
Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation |
title_fullStr |
Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation |
title_full_unstemmed |
Vitamin B12 deficiency causing neurological syndrome with rare skin manifestation |
title_sort |
vitamin b12 deficiency causing neurological syndrome with rare skin manifestation |
publisher |
Deccan College of Medical Sciences |
series |
Journal of Medical and Allied Sciences |
issn |
2231-1696 2231-170X |
publishDate |
2018-01-01 |
description |
Vitamin B12 is an essential vitamin for metabolism of carbohydrates, protein and fat. It is also required for proper functioning of nervous system. Skin hyper pigmentation, hair changes, vitiligo and angular stomatitis are cutaneous manifestations of vitamin B12 deficiency. Hyper pigmentation in Indian patients as first presentation of this deficiency is rarely reported. Our case was a 39-year-old lady who has presented with selective dark hyperpigmentation of hands and feet with electrophysiological evidence of peripheral neuropathy and biochemically proven vitamin B12 deficiency. Skin manifestation was reversed with intramuscular vitamin B12 administration of 1000mcg for 6 weeks. This case emphasizes the importance of rare skin presentation of reversible condition. It also marks the necessity of understanding all aspects and presentations of vitamin B12. Role of nutritional aspects of a person and their importance to prevent neurological sequel is discussed. [J Med Allied Sci 2018; 8(1.000): 49-52] |
topic |
Cutaneous manifestations Neurological manifestations Vitamin B12 deficiency |
url |
http://www.ejmanager.com/fulltextpdf.php?mno=275238 |
work_keys_str_mv |
AT samreenfathima vitaminb12deficiencycausingneurologicalsyndromewithrareskinmanifestation AT tukaramumesh vitaminb12deficiencycausingneurologicalsyndromewithrareskinmanifestation |
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