A Three years retrospective analysis of agents isolated from cerebrospinal fluid in a University Hospital
Objectives: In this study, we aimed to investigate the agents which were isolated from cerebrospinal fluid (CSF) samples in our hospital for three years, retrospectively.Materials and methods: The CSF samples, which were sent our laboratory, of the patients those had presumptive diagnosis of meningi...
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doaj-c586b0d1c40f452c91d5dedbac7711e42020-11-25T01:13:01ZengDicle University Medical SchoolDicle Medical Journal 1300-29451308-98892012-03-013917074A Three years retrospective analysis of agents isolated from cerebrospinal fluid in a University HospitalBarış OtluNilay GüçlüerMehmet Sait TekerekoğluYusuf YakupoğullarıYücel DumanObjectives: In this study, we aimed to investigate the agents which were isolated from cerebrospinal fluid (CSF) samples in our hospital for three years, retrospectively.Materials and methods: The CSF samples, which were sent our laboratory, of the patients those had presumptive diagnosis of meningitis between September 2008 and September 2011 were included into the study. Isolated bacteria were identified with conventional methods, biochemical tests and/or Phonix (BD, US) kits. Antimicrobial susceptibility of the strains were investigated according to Clinical Laboratory Standards Institute (CLSI) recommendations.Results: 11 Streptococcus pneumoniae, 8 Klebsiella pneumoniae, 7 Pseudomonas aeruginosa, 7 Acinetobacter baumannii, 5 Escherichia coli, 4 Enterococcus spp., 2 Enterobacter spp., 25 Coagulase-negative staphylococcus, 1 Morganella morganii, 2 Neisseria meningitidis, 1 Brucella spp., and 1 Candida albicans were isolated (overall n:74; 5.2%) from total 1408 CSF samples. In susceptibility test, 2 S.pneumonia was found as penicillin-resistant, and one E.coli and two K.pneumoniae were found as extended spectrum of beta-lactamase producers. Additionally, carbapenem resistance was detected in three A.baumannii and one P.aeruginosa strains.Conclusion: Determination of agent profile and antimicrobial resistance pattern from different localizations and patients’ groups will help to improve protective and therapeutic health policies.http://www.diclemedj.org/upload/sayi/1/DicleMedJ-01093.pdfMeningitiscerebrospinal fluidantimicrobial susceptibility |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Barış Otlu Nilay Güçlüer Mehmet Sait Tekerekoğlu Yusuf Yakupoğulları Yücel Duman |
spellingShingle |
Barış Otlu Nilay Güçlüer Mehmet Sait Tekerekoğlu Yusuf Yakupoğulları Yücel Duman A Three years retrospective analysis of agents isolated from cerebrospinal fluid in a University Hospital Dicle Medical Journal Meningitis cerebrospinal fluid antimicrobial susceptibility |
author_facet |
Barış Otlu Nilay Güçlüer Mehmet Sait Tekerekoğlu Yusuf Yakupoğulları Yücel Duman |
author_sort |
Barış Otlu |
title |
A Three years retrospective analysis of agents isolated from cerebrospinal fluid in a University Hospital |
title_short |
A Three years retrospective analysis of agents isolated from cerebrospinal fluid in a University Hospital |
title_full |
A Three years retrospective analysis of agents isolated from cerebrospinal fluid in a University Hospital |
title_fullStr |
A Three years retrospective analysis of agents isolated from cerebrospinal fluid in a University Hospital |
title_full_unstemmed |
A Three years retrospective analysis of agents isolated from cerebrospinal fluid in a University Hospital |
title_sort |
three years retrospective analysis of agents isolated from cerebrospinal fluid in a university hospital |
publisher |
Dicle University Medical School |
series |
Dicle Medical Journal |
issn |
1300-2945 1308-9889 |
publishDate |
2012-03-01 |
description |
Objectives: In this study, we aimed to investigate the agents which were isolated from cerebrospinal fluid (CSF) samples in our hospital for three years, retrospectively.Materials and methods: The CSF samples, which were sent our laboratory, of the patients those had presumptive diagnosis of meningitis between September 2008 and September 2011 were included into the study. Isolated bacteria were identified with conventional methods, biochemical tests and/or Phonix (BD, US) kits. Antimicrobial susceptibility of the strains were investigated according to Clinical Laboratory Standards Institute (CLSI) recommendations.Results: 11 Streptococcus pneumoniae, 8 Klebsiella pneumoniae, 7 Pseudomonas aeruginosa, 7 Acinetobacter baumannii, 5 Escherichia coli, 4 Enterococcus spp., 2 Enterobacter spp., 25 Coagulase-negative staphylococcus, 1 Morganella morganii, 2 Neisseria meningitidis, 1 Brucella spp., and 1 Candida albicans were isolated (overall n:74; 5.2%) from total 1408 CSF samples. In susceptibility test, 2 S.pneumonia was found as penicillin-resistant, and one E.coli and two K.pneumoniae were found as extended spectrum of beta-lactamase producers. Additionally, carbapenem resistance was detected in three A.baumannii and one P.aeruginosa strains.Conclusion: Determination of agent profile and antimicrobial resistance pattern from different localizations and patients’ groups will help to improve protective and therapeutic health policies. |
topic |
Meningitis cerebrospinal fluid antimicrobial susceptibility |
url |
http://www.diclemedj.org/upload/sayi/1/DicleMedJ-01093.pdf |
work_keys_str_mv |
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