Chlamydial Protease-Like Activity Factor and Type III Secreted Effectors Cooperate in Inhibition of p65 Nuclear Translocation

Chlamydial Protease-Like Activity Factor and Type III Secreted Effectors Cooperate in Inhibition of p65 Nuclear Translocation

The chlamydial protease-like activity factor (CPAF) is hypothesized to be an important secreted virulence factor; however, challenges in denaturing its proteolytic activity have hampered attempts to identify its legitimate targets. Here, we use a genetic and proteomic approach to identify authentic...

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Bibliographic Details
Main Authors: Michael John Patton, Stuart McCorrister, Chris Grant, Garrett Westmacott, Robert Fariss, Pingzhao Hu, Kaiqiong Zhao, Mary Blake, Bill Whitmire, Chunfu Yang, Harlan D. Caldwell, Grant McClarty
Format: Article
Language:English
Published: American Society for Microbiology 2016-09-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/5/e01427-16

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http://mbio.asm.org/cgi/content/full/7/5/e01427-16

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