Chemical constituents of the wood from Zanthoxylum quinduense Tul. (Rutaceae)

• Main Authors: Oscar Javier Patiño Ladino, Luis Enrique Cuca Suárez
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Química 2010-01-01
• Series: Química Nova
• Subjects: Zanthoxylum quinduense; benzophenanthridine alkaloids; antifungal activity
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000500002

Phytochemical investigation of the wood from Zanthoxylum quinduense Tul. allowed the isolation and identification of norchelerythrine, decarine, 6-acetonyldihydrochelerythrine, syringaresinol, evofilin C, p-hydroxybenzaldehyde, vanillic acid, a mixture of β-sitosterol, stigmasterol and campesterol and a mixture of saturated and unsaturated fatty acids, and their esters derivatives. The structures of the isolated compounds were elucidated by spectroscopic techniques and comparison with literature data and the mixture of sterols and fatty acids were identified by GC/MS. The antifungal activity of the ethanolic extract, fractions and pure compounds against Fusarium oxysporum f. sp. lycopersici was determined by bioautography. Evofilin C and nochelerytrine were the only substances that present antifungal activity.