Transition-Metal-Free C(sp3)–H Oxidation of Diarylmethanes
An efficient direct C(sp3)–H oxidation of diarylmethanes has been demonstrated by this study. This method employs environment-friendly O2 as an oxidant and is promoted by commercially available MN(SiMe3)2 [M = K, Na or Li], which provides a facile method for the synthesis of various diaryl...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-08-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/23/8/1922 |
| id |
doaj-c59640cbe98f4c5ea46d10d2461af8de |
|---|---|
| record_format |
Article |
| spelling |
doaj-c59640cbe98f4c5ea46d10d2461af8de2020-11-24T22:06:50ZengMDPI AGMolecules1420-30492018-08-01238192210.3390/molecules23081922molecules23081922Transition-Metal-Free C(sp3)–H Oxidation of DiarylmethanesFan Yang0Bihui Zhou1Pu Chen2Dong Zou3Qiannan Luo4Wenzhe Ren5Linlin Li6Limei Fan7Jie Li8Department of Pharmacy, School of Medicine, Zhejiang University City College, No. 48, Huzhou Road, Hangzhou 310015, ChinaDepartment of Pharmacy, School of Medicine, Zhejiang University City College, No. 48, Huzhou Road, Hangzhou 310015, ChinaDepartment of Pharmacy, School of Medicine, Zhejiang University City College, No. 48, Huzhou Road, Hangzhou 310015, ChinaDepartment of Pharmacy, School of Medicine, Zhejiang University City College, No. 48, Huzhou Road, Hangzhou 310015, ChinaDepartment of Pharmacy, School of Medicine, Zhejiang University City College, No. 48, Huzhou Road, Hangzhou 310015, ChinaDepartment of Pharmacy, School of Medicine, Zhejiang University City College, No. 48, Huzhou Road, Hangzhou 310015, ChinaDepartment of Pharmacy, School of Medicine, Zhejiang University City College, No. 48, Huzhou Road, Hangzhou 310015, ChinaDepartment of Pharmacy, School of Medicine, Zhejiang University City College, No. 48, Huzhou Road, Hangzhou 310015, ChinaDepartment of Pharmacy, School of Medicine, Zhejiang University City College, No. 48, Huzhou Road, Hangzhou 310015, ChinaAn efficient direct C(sp3)–H oxidation of diarylmethanes has been demonstrated by this study. This method employs environment-friendly O2 as an oxidant and is promoted by commercially available MN(SiMe3)2 [M = K, Na or Li], which provides a facile method for the synthesis of various diaryl ketones in excellent yields. This protocol is metal-free, mild and compatible with a number of functional groups on substrates.http://www.mdpi.com/1420-3049/23/8/1922metal-freediarylmethaneoxidationketone |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Fan Yang Bihui Zhou Pu Chen Dong Zou Qiannan Luo Wenzhe Ren Linlin Li Limei Fan Jie Li |
| spellingShingle |
Fan Yang Bihui Zhou Pu Chen Dong Zou Qiannan Luo Wenzhe Ren Linlin Li Limei Fan Jie Li Transition-Metal-Free C(sp3)–H Oxidation of Diarylmethanes Molecules metal-free diarylmethane oxidation ketone |
| author_facet |
Fan Yang Bihui Zhou Pu Chen Dong Zou Qiannan Luo Wenzhe Ren Linlin Li Limei Fan Jie Li |
| author_sort |
Fan Yang |
| title |
Transition-Metal-Free C(sp3)–H Oxidation of Diarylmethanes |
| title_short |
Transition-Metal-Free C(sp3)–H Oxidation of Diarylmethanes |
| title_full |
Transition-Metal-Free C(sp3)–H Oxidation of Diarylmethanes |
| title_fullStr |
Transition-Metal-Free C(sp3)–H Oxidation of Diarylmethanes |
| title_full_unstemmed |
Transition-Metal-Free C(sp3)–H Oxidation of Diarylmethanes |
| title_sort |
transition-metal-free c(sp3)–h oxidation of diarylmethanes |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2018-08-01 |
| description |
An efficient direct C(sp3)–H oxidation of diarylmethanes has been demonstrated by this study. This method employs environment-friendly O2 as an oxidant and is promoted by commercially available MN(SiMe3)2 [M = K, Na or Li], which provides a facile method for the synthesis of various diaryl ketones in excellent yields. This protocol is metal-free, mild and compatible with a number of functional groups on substrates. |
| topic |
metal-free diarylmethane oxidation ketone |
| url |
http://www.mdpi.com/1420-3049/23/8/1922 |
| work_keys_str_mv |
AT fanyang transitionmetalfreecsp3hoxidationofdiarylmethanes AT bihuizhou transitionmetalfreecsp3hoxidationofdiarylmethanes AT puchen transitionmetalfreecsp3hoxidationofdiarylmethanes AT dongzou transitionmetalfreecsp3hoxidationofdiarylmethanes AT qiannanluo transitionmetalfreecsp3hoxidationofdiarylmethanes AT wenzheren transitionmetalfreecsp3hoxidationofdiarylmethanes AT linlinli transitionmetalfreecsp3hoxidationofdiarylmethanes AT limeifan transitionmetalfreecsp3hoxidationofdiarylmethanes AT jieli transitionmetalfreecsp3hoxidationofdiarylmethanes |
| _version_ |
1725821565509042176 |